The conjugate addition reactions of -1,2-di(2-pyridyl)ethylene have been studied. This substrate reacts with organolithium nucleophiles, and the resulting anionic intermediates may be trapped by proton or various carbonyl-based electrophiles. It is suggested that the dipyridyl structure stabilizes the intermediate carbanion, allowing the Michael adduct to be captured by an added electrophile.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781395 | PMC |
| http://dx.doi.org/10.1021/acs.joc.0c00823 | DOI Listing |
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