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Bone Marrow Aspiration Concentrate in the Treatment of Osteoarthritis: A Review of its Current Clinical Application.
Tissue Eng Regen Med
January 2025
Department of Orthopaedics, Dongguk University Ilsan Hospital, Dongguk-Ro 27, Goyang, Republic of Korea.
Background: Bone marrow aspiration concentrate (BMAC) has gained acceptance as a safe orthobiologic for treating osteoarthritis (OA), despite lacking robust supporting evidence. Although several publications have documented the use of BMAC in OA, evidence confirming its unequivocal efficacy remains limited.
Methods: This review aims to summarize the current clinical evidence regarding BMAC as a therapeutic for OA, while also presenting the author's perspective.
Comprehensive Chlorine Suppression: Advances in Materials and System Technologies for Direct Seawater Electrolysis.
Nanomicro Lett
January 2025
State Key Laboratory of Heavy Oil Processing, College of New Energy, China University of Petroleum (East China), Qingdao, 266580, People's Republic of China.
Seawater electrolysis offers a promising pathway to generate green hydrogen, which is crucial for the net-zero emission targets. Indirect seawater electrolysis is severely limited by high energy demands and system complexity, while the direct seawater electrolysis bypasses pre-treatment, offering a simpler and more cost-effective solution. However, the chlorine evolution reaction and impurities in the seawater lead to severe corrosion and hinder electrolysis's efficiency.
View Article and Find Full Text PDFConjugation of PDLA onto MgO microspheres: comparison between solution grafting and melt grafting methods.
J Mater Chem B
January 2025
Engineering Research Centre for Biomedical Materials of Ministry of Education, Key Laboratory for Ultrafine Materials of Ministry of Education, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, China.
Magnesium oxide (MgO) is known for its bioactivity and osteoconductivity when incorporated into biodegradable poly(lactic acid) (PLA), whereas the weak interfacial bonding between MgO microspheres (mMPs) and PLA often leads to suboptimal composite properties with uncontrollable functionality. Conjugation of mMPs with PLA may offer a good way to enhance their compatibility. In this study, we systematically investigated two grafting techniques, solution grafting (Sol) and melt grafting (Mel), to decorate poly (D-lactic acid) (PDLA) on mMPs pre-treated by prioritized hydration to obtain Sol MPs and Mel MPs, in order to optimize the grafting efficiency and improve their controllability in the properties including the crystal structure and surface morphology.
View Article and Find Full Text PDFDynamics of Pyrene Excimer in a Cholesteryl-based Supramolecular Host Matrix.
Chemphyschem
January 2025
IISER Bhopal: Indian Institute of Science Education and Research Bhopal, Department of Chemistry, Bhopal Bypass Road, Bhauri, 462066, Bhopal, INDIA.
Aggregation-caused quenching (ACQ) reduces luminescence and compromises brightness in solid-state displays, necessitating strategies to mitigate its effects for enhanced performance. This study presents cost-effective method to mitigate ACQ of pyrene by co-assembling polycyclic aromatic hydrocarbons within low molecular weight gelator. Synthesized from readily available materials-cholesteryl chloroformate and pentaerythritol-in one-step reaction, gelator incorporates four cholesteryl units, reported to promote robust supramolecular gels in various solvents.
View Article and Find Full Text PDFPrevalence and Risk Factors for Medial Meniscus Ramp Lesions in the Setting of Pediatric Anterior Cruciate Ligament Injuries: A Systematic Review and Meta-analysis.
J Pediatr Orthop
January 2025
Department of Pediatric Orthopedic Surgery, Hospital for Special Surgery, New York, NY.
Background: Medial meniscus ramp lesions (MMRLs) are commonly associated with anterior cruciate ligament (ACL) injuries and may increase the risk of graft failure after ACL reconstruction (ACLR) if undiagnosed or left untreated. Although MMRLs have been extensively reported in adults, there are limited studies describing them in pediatric patients undergoing ACLR. The purpose of this study was to perform a systematic review and meta-analysis to determine the pooled prevalence of and risk factors for MMRLs in pediatric patients with ACL injuries.
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