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Rethinking Optimal Immunogens to Face SARS-CoV-2 Evolution Through Vaccination.
Influenza Other Respir Viruses
January 2025
Área de Investigación en Vacunas, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana, Valencia, Spain.
SARS-CoV-2, which originated in China in late 2019, quickly fueled the global COVID-19 pandemic, profoundly impacting health and the economy worldwide. A series of vaccines, mostly based on the full SARS-CoV-2 Spike protein, were rapidly developed, showing excellent humoral and cellular responses and high efficacy against both symptomatic infection and severe disease. However, viral evolution and the waning humoral neutralizing responses strongly challenged vaccine long term effectiveness, mainly against symptomatic infection, making necessary a strategy of repeated and updated booster shots.
View Article and Find Full Text PDFUnmet Social Needs of Older Adults With Mobility Limitations Following Inpatient Rehabilitation Discharge in Nigeria: A Qualitative Narrative Inquiry Study.
J Geriatr Phys Ther
January 2025
Emerging Researchers & Professionals in Aging-African Network, Nigeria & Canada.
Background And Purpose: Approximately, 30% to 60% of older adults experience functional decline following hospitalization, which has implications for their ability to meet social needs after discharge. Exploring the unmet social needs of older adults following discharge is warranted to rethink the elements of hospital discharge in low-resource countries. This study explored the unmet social needs of older adults with mobility limitations following discharge from an inpatient rehabilitation unit in a state hospital in Northern Nigeria.
View Article and Find Full Text PDFLombardy Region: seven years of breast cancers screening before, during and after the SARS-CoV-2 pandemic.
Ann Ig
January 2025
Department of Biomedical Sciences for Health, University of Milan, Italy.
Background: Breast cancer represents the most common form of neoplasm in women, with an estimated 685,000 deaths annually. In this regard, screening programmes represent one of the most effective intervention tools in the field of cancer prevention. The aim of this study is to analyse and describe the key performance indicators of the screening programmes in Lombardy from 2016 to 2022.
View Article and Find Full Text PDFAntiscience, Vaccine Hesitancy, and Pandemic Responses: Highlights from the Asia Pacific Summit on Infectious Diseases and Immunization.
Vaccines (Basel)
November 2024
Asia-Pacific Immunization Coalition, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
The recent resurgence of mpox highlights the urgent need for rethinking vaccination strategies globally, underscored by the painful memories of past public health crises where delayed responses and inequitable vaccine distribution exacerbated the spread of infectious diseases. The inaugural APIC-ADVA Asia Pacific Summit on Infectious Diseases and Immunization, themed "Vaccination for All: Access, Confidence and Equity (ACE)", was held in Singapore from 31 October to 1 November 2023 in an attempt to present best practices and hard-won insights from battling COVID-19 and other pandemics in the Asia-Pacific region. This summit was co-convened by the Asia-Pacific Immunization Coalition (APIC) and Asia Dengue Voice and Action (ADVA).
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