Physical reservoir computing approaches have gained increased attention in recent years due to their potential for low-energy high-performance computing. Despite recent successes, there are bounds to what one can achieve simply by making physical reservoirs larger. Therefore, we argue that a switch from single-reservoir computing to multi-reservoir and even deep physical reservoir computing is desirable. Given that error backpropagation cannot be used directly to train a large class of multi-reservoir systems, we propose an alternative framework that combines the power of backpropagation with the speed and simplicity of classic training algorithms. In this work we report our findings on a conducted experiment to evaluate the general feasibility of our approach. We train a network of 3 Echo State Networks to perform the well-known NARMA-10 task, where we use intermediate targets derived through backpropagation. Our results indicate that our proposed method is well-suited to train multi-reservoir systems in an efficient way.
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http://dx.doi.org/10.1038/s41598-020-71549-y | DOI Listing |
Adv Healthc Mater
January 2025
School of Pharmacy, Queen's University Belfast, Lisburn Road 97, Belfast, BT9 7BL, UK.
Implantable drug delivery systems are crucial for achieving sustained delivery of active compounds to specific sites or systemic circulation. In this study, a novel reservoir-type implant combining a biodegradable rate-controlling membrane with a drug-containing core prepared using direct compression techniques is developed. The membrane is composed of poly(caprolactone) (PCL), and risperidone (RIS) served as the model drug.
View Article and Find Full Text PDFLab Chip
January 2025
Electrical and Computer Engineering, University of Canterbury, 20 Kirkwood Avenue, Ilam, Christchurch, New Zealand.
New flow control elements in capillaric circuits are key to achieving ever more complex lab-on-a-chip functionality while maintaining their autonomous and easy-to-use nature. Capillary field effect transistors valves allow for flow in channels to be restricted and cut off utilising a high pressure triggering channel and occluding air bubble. The reversible capillary field effect transistor presented here provides a new element that can restore fluid flow in closed microchannels autonomous circuit feedback.
View Article and Find Full Text PDFMed Gas Res
January 2025
McLean Hospital, Harvard Medical School, Belmont, MA, USA.
Xenon gas is considered to be a safe anesthetic and imaging agent. Research on its other potentially beneficial effects suggests that xenon may have broad efficacy for treating health disorders. A number of reviews on xenon applications have been published, but none have focused on substance use disorders.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Department for Functional Materials in Medicine and Dentistry, University Hospital Würzburg, Würzburg, Germany.
Studying the molecular basis of intestinal infections caused by enteric pathogens at the tissue level is challenging, because most human intestinal infection models have limitations, and results obtained from animals may not reflect the human situation. Infections with Salmonella enterica serovar Typhimurium (STm) have different outcomes between organisms. 3D tissue modeling of primary human material provides alternatives to animal experimentation, but epithelial co-culture with immune cells remains difficult.
View Article and Find Full Text PDFSci Rep
January 2025
State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation, Southwest Petroleum University, Chengdu, 610500, China.
The exploration and development of deep marine shale gas has made significant breakthroughs, but factors influencing gas contents of deep marine shale are elusive, and quantitative prediction methods of gas content needs to be refined urgently. In this study, the deep marine shale of Longmaxi Formation in Luzhou area was taken as an example, vitrinite reflectance analysis, kerogen microscopy experiment, TOC content analysis, mineral composition analysis, gas content measurement, isothermal adsorption experiment, physical property analysis and argon ion polishing scanning electron microscopy experiment were carried out to find out factors affecting the gas content of deep marine shale, and a gas content prediction model has been worked out. Conclusions below have been reached: the content of adsorbed gas is mainly affected by Ro, TOC content, porosity, water saturation, clay mineral content, formation temperature and pressure; the content of free gas is mainly controlled by porosity, water saturation, formation temperature and pressure; according to the prediction models, the adsorbed gas content, free gas content and total gas content of each well were quantitatively calculated, and the study area was divided into Class I (with a total gas content ≥ 11 m/t), Class II (with a total gas content between 9 m/t and 11 m/t), and Class III (with a total gas content < 9 m/t) gas-bearing areas.
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