AI Article Synopsis
- - Rotavirus A (RVA) causes severe diarrhea in humans and animals, with animal-to-human transmission contributing to strain diversity in humans.
- - In a study, feces from 416 bats were tested for RVA, revealing a 7% prevalence in Pteropus medius and 2% in Rousettus leschenaultii, while no RVA was found in Taphozous melanopogon.
- - The identified RVA strains in bats were similar to those found in humans (G1 and G8), highlighting the need for monitoring wildlife to understand how zoonotic pathogens evolve and spread.
Article Abstract
Rotavirus A (RVA) is the primary cause of acute dehydrating diarrhea in human and numerous animal species. Animal-to-human interspecies transmission is one of the evolutionary mechanisms driving rotavirus strain diversity in humans. We screened fresh feces from 416 bats (201 Pteropus medius, 165 Rousettus leschenaultii and 50 Taphozous melanopogon) for RVA using rRT-PCR. We detected a prevalence of 7% (95% CI 3.5-10.8) and 2% (95% CI 0.4-5.2) in P. medius and R. leschenaultii, respectively. We did not detect RVA in the insectivorous bat (T. melanopogon). We identified RVA strains similar to the human strains of G1 and G8 based on sequence-based genotyping, which underscores the importance of including wildlife species in surveillance for zoonotic pathogens to understand pathogen transmission and evolution better.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464061 | PMC |
| http://dx.doi.org/10.1007/s10393-020-01488-7 | DOI Listing |
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