AI Article Synopsis
- The introduction of FOLFIRINOX and neoadjuvant radiotherapy has broadened surgical options for patients with pancreatic adenocarcinoma.
- Patients with advanced tumors in the body/tail of the pancreas, particularly those affecting the celiac trunk but responding well to neoadjuvant treatments, may qualify for a modified Appleby procedure.
- Successful execution of this complex surgery demands careful patient selection, skilled surgeons, and interventional radiology expertise.
Article Abstract
With the advent of FOLFIRINOX and neoadjuvant radiotherapy, the surgical indications for adenocarcinoma have expanded. Locally advanced pancreatic adenocarcinomas of the body/tail with infiltration of the celiac trunk which have a good clinical, biological, and radiological response to neoadjuvant treatment may therefore be eligible for caudal pancreatectomy with resection of the celiac trunk (modified Appleby procedure). In addition to rigorous patient selection and surgical expertise, this procedure also requires experience in interventional radiology.
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| http://dx.doi.org/10.1007/s11605-020-04782-5 | DOI Listing |
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