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miR-181a/MSC-Loaded Nano-Hydroxyapatite/Collagen Accelerated Bone Defect Repair in Rats by Targeting Ferroptosis Pathway.
J Funct Biomater
December 2024
Hospital of Stomatology, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
: The reparative regeneration of jawbone defects poses a significant challenge within the field of dentistry. Despite being the gold standard, autogenous bone materials are not without drawbacks, including a heightened risk of postoperative infections. Consequently, the development of innovative materials that can surpass the osteogenic capabilities of autologous bone has emerged as a pivotal area of research.
View Article and Find Full Text PDFBeyond Bone Grafts: Exploring the Efficacy of Alternative Regenerative Therapies.
Cureus
November 2024
Department of Periodontology and Dental Implantology, Medical University of Varna, Varna, BGR.
Context A vast body of published literature examines and evaluates the properties of bone restorative materials in combination with other biomaterials or as stand-alone applications. If we exclude the studies investigating the effectiveness of regenerative therapy with enamel matrix derivative (EMD), in all other cases, bone regenerative materials are placed on a "pedestal." Therefore, the study we have initiated covers methods whose protocol does not use bone-repair materials.
View Article and Find Full Text PDFEfficacy of bioresorbable mesh sheets made of 85:15 poly(lactic-co-glycolic acid) in the anterior maxilla for alveolar bone augmentation.
J Oral Implantol
December 2024
Professor, Department of Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
This study evaluated the efficacy of poly(lactic-co-glycolic acid) (PLGA) mesh sheets for alveolar bone reconstruction in the anterior maxilla with significant bone defects. This prospective case series included four male patients (mean age, 34.5 years; range, 20-49 years) with anterior maxillary bone defects.
View Article and Find Full Text PDFInvestigating the Efficacy of Regenerative Therapy With Autogenous Platelet-Rich Plasma in Vertical Bone Defects.
Cureus
October 2024
Periodontology and Dental Implantology, Medical University of Varna, Varna, BGR.
Context and objective The main goal of periodontal therapy is to remove periodontopathogenic microorganisms and regenerate destructured periodontal tissues. Advances in biomaterials have improved the results of regenerative procedures. However, there is limited data available to determine the best material for vertical bone deformities treated with regenerative treatment.
View Article and Find Full Text PDFFish: a new xenograft source for maxillary sinus lifting.
J Appl Oral Sci
November 2024
Erciyes University, Faculty of Medicine, Department of Histology and Embryology, Kayseri, Türkiye.
Objective: Although autogenous grafting is accepted as the gold standard in intraoral grafting, xenogenous grafts are frequently used in sinus lift surgeries due to their osteoinductive and osteoconductive properties. This study aimed to investigate the efficacy of fish spine-derived xenogenic grafts in sinus augmentation surgery.
Material And Methods: In this study, a fish spine-derived xenogenic graft was produced for comparison with autogenous graft and bovine derived xenogenic grafts.
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