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Outcomes of Revision Cartilage Restoration Surgery for Failed Primary Treatment of Chondral or Osteochondral Defects of the Knee: A Systematic Review.
Am J Sports Med
January 2025
Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York, USA.
Background: Failure of primary cartilage restoration procedures of the knee that proceed to necessitating revision cartilage procedures represent a challenging clinical scenario with variable outcomes reported in previous literature.
Purpose: To perform a systematic review and meta-analysis of clinical outcomes and adverse events after revision cartilage restoration procedures of the knee for failed primary cartilage procedures.
Study Design: Systematic review and meta-analysis; Level of evidence, 4.
Enhancing Rotator Cuff Repair in Rabbit Osteoporosis With Chitosan Quaternary Ammonium Salt-Coated Nickel-Titanium Memory Alloy Anchors.
Am J Sports Med
January 2025
Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou, Gansu, P.R. China.
Background: For patients with osteoporosis and rotator cuff tears, there is still no consensus on current treatment methods. The material, structure, and number of anchors have important effects on the repair outcome.
Purpose: To investigate the use of chitosan quaternary ammonium salt-coated nickel-titanium memory alloy (NTMA) anchors to treat rotator cuff injury in shoulders with osteoporosis in a rabbit osteoporosis model.
Fixation of an Osteochondral Fragment with Autologous Bone Picks in the Knee - A Case Report.
Rev Bras Ortop (Sao Paulo)
November 2024
Ortopedia e Traumatologia, Hospital Universitário de Santa Maria, Santa Maria, RS, Brasil.
Osteochondral injuries in the knee are uncommon in the immature skeleton and are usually related to sporting activities. Fixation is required depending on the size and location of the fragment. The standard technique is open reduction and internal fixation with metal screws, which are removed in a second procedure after consolidation.
View Article and Find Full Text PDFLocal delivery of TGF-β1-mRNA decreases fibrosis in osteochondral defects.
Bioact Mater
March 2025
Department of Orthopedics and Rehabilitation, USA.
Osteoarthritis (OA) is a condition that affects the quality of life of millions of patients worldwide. Current clinical treatments, in most cases, lead to cartilage repair with deposition of fibrocartilage tissue, which is mechanically inferior and not as durable as hyaline cartilage tissue. We designed an mRNA delivery strategy to enhance the natural healing potential of autologous bone marrow aspirate concentrate (BMAC) for articular cartilage repair.
View Article and Find Full Text PDFSecond-Look Needle Arthroscopy After Prior Surgical Treatment for Cartilage Lesions of the Ankle: The Amsterdam and New York City Perspectives.
Cartilage
December 2024
Department of Orthopedic Surgery and Sports Medicine, Amsterdam UMC, Location University of Amsterdam, Amsterdam, The Netherlands.
Objective: The purpose of this prospective study was to evaluate the quality of the reparative cartilage during second-look needle arthroscopy following talar osteoperiostic grafting from the iliac crest (TOPIC) or autologous osteochondral transplantation (AOT) procedure for the management of large osteochondral lesions (OCLs) of the talus.
Design: Prospective case series.
Methods: Patients who underwent second-look needle arthroscopy following either TOPIC or AOT procedure were prospectively recruited when they needed a second look.
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