AI Article Synopsis
- - Francisella tularensis subsp. holarctica is a dangerous bacteria that causes tularemia, affecting mainly lagomorphs like rabbits and rodents, with increasing human cases in Switzerland over the last 5 years.
- - The study reports the first identification of this bacteria from a domestic cat in Europe, marking a significant finding in the understanding of its spread.
- - Genetic analysis reveals that the cat's isolate is closely related to a hare isolate from the same area, suggesting a potential link in the disease's transmission between species.
Article Abstract
Francisella tularensis subsp. holarctica is a select agent causing life-threatening tularemia. It has been isolated from humans and animals, mainly lagomorphs and rodents, rarely other wild carnivore species. Increasing numbers of human tularemia cases have been reported during the last 5 years in Switzerland. Here we report the first isolation of Francisella tularensis subsp. holarctica from a domestic cat in Europe and compare its genome sequence with other Swiss isolates. The cat isolate shows a close phylogenetic relationship with a contemporary hare isolate from close geographic proximity, indicating a possible epidemiological link.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457513 | PMC |
| http://dx.doi.org/10.1186/s13567-020-00834-5 | DOI Listing |
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