N-heterocyclic carbenes (NHCs) are well-known as ligands and organocatalysts, but there is no recognition for their catalytic role as a stabilizer through electrostatic interaction rather than electron donation. By utilizing the electrostatic interaction, we herein describe the success of a visible-light-triggered radical-radical cross-coupling of N-alkenoxypyridinium salts and NaI, giving a variety of α-iodo ketones. Computational studies characterize the stabilization role of NHCs.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.orglett.0c02523 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Polydopamine-Mediated, Centrifugal Force-Driven Gold Nanoparticle-Deposited Microneedle SERS Sensors for Food Safety Monitoring Theoretical Study of the SERS Substrate Fabrication.
ACS Sens
January 2025
The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, and Department of Chemistry, Shanghai Normal University, Shanghai 200234, P. R. China.
Microneedle (MN) sensors have great promise for food safety detection, but the rapid preparation of MNs for surface-enhanced Raman scattering (SERS) sensors with tunable and homogeneous nanoparticles remains a great challenge. To address this, a SERS sensor of gold nanoparticles@polydopamine@poly(methyl methacrylate) MN (AuNPs@PDA@PMMA-MN) was developed. The extended-Derjaguin-Landau-Verwey-Overbeek theory was applied to calculate the interaction energy between AuNPs and PDA.
View Article and Find Full Text PDFModeling the navigating forces behind BSA aggregation in a microfluidic chip.
Soft Matter
January 2025
Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
Microfluidic chips are powerful tools for investigating numerous variables including chemical and physical parameters on protein aggregation. This study investigated the aggregation of bovine serum albumin (BSA) in two different systems: a vial-based static system and a microfluidic chip-based dynamic system in which BSA aggregation was induced successfully. BSA aggregation induced in a microfluidic chip on a timescale of seconds enabled a dynamic investigation of the forces driving the aggregation process.
View Article and Find Full Text PDFHydrogen Bonding-Driven Adaptive Coacervates as Protocells.
ACS Appl Mater Interfaces
January 2025
Key Laboratory of Colloid and Interface Chemistry of the Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong 250100, China.
Coacervation based on liquid-liquid phase separation (LLPS) has been widely used for the preparation of artificial protocells and to mimic the dynamic organization of membrane-free organelles. Most complex synthetic coacervates are formed through electrostatic interactions but cannot withstand high ionic strength conditions (>0.1 M).
View Article and Find Full Text PDFEvidence of strong O-H⋯C interactions involving apical pyramidane carbon atoms as hydrogen atom acceptors.
Phys Chem Chem Phys
January 2025
University of Belgrade - Faculty of Chemistry, Studentski trg 12-16, Belgrade, Serbia.
Using high-level quantum chemical calculations, we predicted a strong O-H⋯C interaction between the apical carbon atoms of pyramidane and its derivatives and water molecules. Analysis of calculated electrostatic potential maps showed that there are areas of strong negative potential above apical carbon atoms in all studied structures. The results of quantum chemical calculations showed that the O-H⋯C interaction between the hydrogen atom of water and the apical carbon atom of pyramidane derivatives with four -CH substituents is unexpectedly strong, Δ = -7.
View Article and Find Full Text PDFEnvironmentally tolerant multifunctional eutectogel for highly sensitive wearable sensors.
Mater Horiz
January 2025
Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu 610031, China.
Article Synopsis
- Flexible hydrogel sensors have limitations in sensitivity and freezing in low temperatures, hindering their applications.
- A new multifunctional eutectogel is developed through photopolymerization, offering properties like high transparency, anti-freezing, and self-healing.
- This eutectogel shows exceptional performance with a high gauge factor for strain sensitivity, making it promising for flexible electronics in cold conditions.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!