Aim: To evaluate surgical treatment options, complications and neurological outcomes of patients with cavernous malformations (CMs) in the pons and medulla oblongata.
Material And Methods: We retrospectively evaluated 25 brain stem CMs that we operated between 2009 and 2019. We operated all cases in the first month with suboccipital retrosigmoid and paramedian approach. The cases were evaluated concerning their demographic characteristics, lesion characteristics, radiological imaging results, surgical approach and neurological status.
Results: Overall, 15 patients had CMs in the pons and 10 in the medulla oblongata. The mean age of the patients was 33.48 years, and the cases included 15 male and 10 female patients. The average modified Rankin Score (mRS) score had a mean of 2.36 and median of 2 at the time of admission (Table I). The mean follow-up period was 4.64 years (1?10 years). In the last follow-up assessment, the average mRS score was mean = 1.84 and median = 1. In addition, 14 (56%) patients recovered, 7 (28%) did not show any changes, 3 (12%) got worse, and 1 (4%) died. In our case series, the admission complaints were cranial nerve paralysis (24%) in 6 cases, nausea and vomiting in 1 (4%) and hemiparesis in 17 (68%).
Conclusion: Experience, correct surgical approach and good knowledge of neuroanatomy are important in brainstem CM haemorrhages. Imaging methods, neuronavigation and neuromonitoring use are essential for patients undergoing surgery. In the presence of all these factors, the prognosis of patients will be better.
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http://dx.doi.org/10.5137/1019-5149.JTN.31207-20.2 | DOI Listing |
J Neurosurg Case Lessons
August 2024
Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Background: Craniotomy is required for the removal of brainstem cavernous malformations (CMs) with repeated hemorrhage, and this condition is often complicated by an accompanying developmental venous anomaly (DVA). However, a DVA of the brainstem or cerebellum with drainage penetrating the pons is an exceptional finding.
Observations: A 57-year-old man presented with double vision.
Dev Psychobiol
November 2023
Department of Clinical Medicine, Turku Brain and Mind Center, FinnBrain Birth Cohort Study, University of Turku, Turku, Finland.
Social touch is closely related to the establishment and maintenance of social bonds in humans, and the sensory brain circuit for gentle brushing is already active soon after birth. Brain development is known to be sexually dimorphic, but the potential effect of sex on brain activation to gentle touch remains unknown. Here, we examined brain activation to gentle skin stroking, a tactile stimulation that resembles affective or social touch, in term-born neonates.
View Article and Find Full Text PDFNeurosurg Rev
September 2023
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
J Neurosurg
February 2024
1Department of Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya City, Aichi, Japan.
Objective: Surgical treatment of brainstem cavernous malformations (CMs) is challenging. Surgery using the endoscopic transsphenoidal transclival approach (eTSTCA) is reported as a useful alternative for ventral brainstem CMs. However, CMs located in the ventral midline of the brainstem are rare, and only a small number of case reports on these CMs treated with the eTSTCA exist.
View Article and Find Full Text PDFNihon Hoshasen Gijutsu Gakkai Zasshi
April 2023
Purpose: The purpose of this study was to investigate the optimal spatial resolution and temporal resolution of dynamic improved motion-sensitized driven-equilibrium steady-state free precession for visualization of respiratory-driven cerebrospinal fluid (CSF) dynamics.
Methods: We investigated the differences in the visualization using the midsagittal cross-sections of nine healthy volunteers by three imaging conditions. (A: spatial resolution 0.
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