Study Design: Systematic review.
Objective: To synthesize studies reporting normative values of active cervical range of motion (ROM) in healthy children and adults.
Summary Of Background Data: Evaluating active cervical ROM is part of routine assessment of patients with neck pain. Interpretation of outcomes necessitates having normative data per age category. Currently available normative values differ across studies, perhaps due to (the measurement properties of) the devices used.
Methods: A systematic review according to PRISMA guidelines was conducted. Electronic searches included EMBASE, MEDLINE, Web of Science, Cochrane, CINAHL and Google Scholar databases from inception to August 2018. Included studies had to involve healthy subjects in which active cervical ROM was assessed or when determining normative values was the aim of the study. Methodological quality of the included studies was assessed using an adapted version of the QUADAS. A mean value was re-calculated for the total group in case data were presented per gender per age-category only. When possible, data were pooled.
Results: From 2151 unique hits, 217 articles were selected for full text assessment, after which 162 articles were excluded. Data were extracted from 55 articles using 16 different measurement devices. Twenty-five studies were rated as being of "low risk of bias". Only data from studies evaluating the CROM device and Zebris could be pooled.
Conclusions: This systematic review revealed that although a large number of studies assessed normative data for active cervical ROM, the methodological quality of most studies was low and the heterogeneity between studies was high. Only the normative data for active cervical ROM using the CROM device seems to be useful. Overall, reference values for measuring active cervical ROM is unclear for most measurement devices. Normative values of cervical range of motion for both children and adults: a systematic review.
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http://dx.doi.org/10.1016/j.msksp.2020.102182 | DOI Listing |
Eur Spine J
January 2025
Exercise Intervention for Health Research Group (EXINH-RG), Department of Physiotherapy, University of Valencia, Valencia, Spain.
Objective: To investigate the prospective associations between age and the risk of low back disorders (LBD), dorsal disorders (DD), and cervical disorders (CD), and to identify a potential age-threshold for increased risk of back disorders.
Methods: Prospective cohort from the UK Biobank comprising adults with no history of back disorders. We examined different ages and their association with the risk of back disorders derived from diagnoses of hospital registers.
Sci Rep
January 2025
Department of Orthopaedic Surgery, School of Medicine, International University of Health and Welfare, 4-3, Kozunomori, Narita, Chiba, 286-8686, Japan.
The occurrence of diseases characterized by irregular spinal alignment, such as kyphosis, lordosis, scoliosis, and dropped head syndrome (DHS) is increasing, particularly among older adults. DHS is characterized by an excessive forward tilt of the head and neck, causing the head to droop. Although it is believed that muscle activity plays a role in both the onset and treatment of DHS, the underlying mechanisms remain unclear.
View Article and Find Full Text PDFJ Stomatol Oral Maxillofac Surg
January 2025
Clinical Genetics Lab, Centre for Cellular and Molecular Research, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India.
Objective: This study aimed to investigate whether NKAP (nuclear factor κB activating protein) serves as a prognostic marker and predictive biomarker for immunotherapy response in head and neck squamous cell carcinoma (HNSCC).
Methods: A retrospective cohort study combined with in vitro analyses was conducted. NKAP mRNA expression levels were assessed in 520 HNSCC tumor tissues and 44 normal tissues from the TCGA dataset and validated in a clinical cohort (n=32).
Introduction: Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease that affects various body systems, including the skin and facial features. Estrogen promotes lupus in human and mouse models of SLE. In this study, we conducted an in vivo study to investigate the relationship between two estrogen receptors (ERα and ERβ) and platelet-activating factor acetylhydrolase (PAF-AH) on the symptoms of SLE.
View Article and Find Full Text PDFHear Res
January 2025
Columbia University Irving Medical Center, Department of Otolaryngology, Head and Neck Surgery, 180 Fort Washington Ave, New York, 10032, NY, USA; Columbia University, Department of Biomedical Engineering, 1210 Amsterdam Ave, New York, 10027, NY, USA.
Sound-evoked displacement responses at the outer hair cell-Deiters' cell junction (OHC-DC) are of significant interest in cochlear mechanics, as OHCs are believed to be in part responsible for active tuning enhancement and amplification. Motion in the cochlea is three-dimensional, and the architecture of the organ of Corti complex (OCC) suggests the presence and mechanical importance of all three components of motion. Optical coherence tomography (OCT) displacement measurements of OHC-DC motion from different experimental preparations often show disparate results, potentially due to OCT measuring only the motion component along the beam axis.
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