Background: Coronavirus disease 2019 (COVID-19) presents with myriad extra-pulmonary manifestation and a high mortality in patients with comorbidities. Its effect on patients with pre-existing acute pancreatitis is not known.
Methods: We hereby, present 3 cases with severe acute pancreatitis with persistent respiratory failure who acquired nosocomial COVID-19 during their hospital stay after recovery from respiratory failure. Their clinical course is highlighted which reflects on pathophysiology of organ dysfunction in these 2 disease states.
Results: None of the 3 patients with severe acute pancreatitis who developed nosocomial COVID-19 redeveloped respiratory failure due to COVID-19 despite having recently recovered from pancreatitis induced acute hypoxemic respiratory failure. Only one patient developed SARS-CoV2 induced moderate pneumonia.
Conclusion: These cases highlight that host responses and mechanisms of lung injury might be different in severe acute pancreatitis and COVID-19.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437538 | PMC |
| http://dx.doi.org/10.1016/j.pan.2020.08.008 | DOI Listing |
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