Novel structures of the human TRPA1 channel were determined in the presence of the agonist iodoacetamide and the antagonist A-967079, to reveal the open and closed states of the channel, respectively. The structures further revealed the location of Ca modulatory site that is likely conserved among several TRP subgroups.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530115 | PMC |
| http://dx.doi.org/10.1016/j.ceca.2020.102278 | DOI Listing |
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