The current stage of development of health systems is characterized by an increasing role of specialists with secondary medical and higher (nursing) education, which imposes additional requirements on their medical, pedagogical, psychological and technical knowledge and skills. The article presents the results of a study implemented in 2019 on the development of medical personnel in the capital's healthcare system. One of the research methods was an expert survey in the form of a series of in-depth structured interviews with the leadership of medical colleges, universities and institutions of additional professional education (N = 15), the scenario of which included blocks of questions regarding the main determinants of the quality of training of nursing staff and bachelors in the direction of "Nursing", as well as ideas for introducing the capital standard of a nurse. The analysis of the information obtained made it possible to identify a number of problems and directions for their solution: at the college level, this is, first of all, poor-quality production practice, which is due to the overload of medical staff and, in general, not serious attitude to trainees, as well as insufficient communication training of future nurses; in the case of undergraduate studies, the main problems are related to students who have gone to university just after school, who have a poor idea of their future profession and are poorly motivated to study in condition when courses that dedicated to studying nursing medical skills, initially aimed at a more professionally trained contingent, have been significantly reduced. Experts, who support the idea of expanding the functions of nurses, the main obstacles to its implementation see in the stereotypes that the chief physicians and the medical community as a whole have about the purely secondary role of the nursing staff, as well as the corresponding attitudes of the nurses themselves. Regarding the standard of the capital's nurse, experts agree that the main emphasis should be on the development of universal competencies, attention to deontological and ethical issues.
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http://dx.doi.org/10.32687/0869-866X-2020-28-s1-680-686 | DOI Listing |
Chimeric antigen receptor (CAR) T-cell products axicabtagene ciloleucel (axi-cel), tisagenlecleucel (tisa-cel), and lisocabtagene maraleucel (liso-cel) are approved for relapsed/refractory large B-cell lymphoma (R/R LBCL). Emerging evidence indicates that delayed CAR T-cell infusion, including prolonged time from leukapheresis to infusion, known as vein-to-vein time (V2Vt), may adversely impact clinical outcomes. We conducted a systematic literature review (SLR) and meta-analysis to identify differences in V2Vt in patients with R/R LBCL treated with axi-cel, tisa-cel, or liso-cel.
View Article and Find Full Text PDFBlood Adv
January 2025
Vanderbilt University Medical Center, Nashville, Tennessee, United States.
In plasma, the zymogens factor XII (FXII) and prekallikrein reciprocally convert each other to the proteases FXIIa and plasma kallikrein (PKa). PKa cleaves high-molecular-weight kininogen (HK) to release bradykinin, which contributes to regulation of blood vessel tone and permeability. Plasma FXII is normally in a "closed" conformation that limits activation by PKa.
View Article and Find Full Text PDFCirculation
January 2025
University of Texas Southwestern Medical Center, Dallas (D.K.M, J.A.d.L., J.A.H).
J Med Internet Res
January 2025
Department High-Tech Business and Entrepreneurship Section, Industrial Engineering and Business Information Systems, University of Twente, Enschede, Overijssel, Netherlands.
Health recommender systems (HRS) have the capability to improve human-centered care and prevention by personalizing content, such as health interventions or health information. HRS, an emerging and developing field, can play a unique role in the digital health field as they can offer relevant recommendations, not only based on what users themselves prefer and may be receptive to, but also using data about wider spheres of influence over human behavior, including peers, families, communities, and societies. We identify and discuss how HRS could play a unique role in decreasing health inequities.
View Article and Find Full Text PDFJ Med Internet Res
January 2025
International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Ibaraki, Japan.
Background: Few studies have explored the relationship between macronutrient intake and sleep outcomes using daily data from mobile apps.
Objective: This cross-sectional study aimed to examine the associations between macronutrients, dietary components, and sleep parameters, considering their interdependencies.
Methods: We analyzed data from 4825 users of the Pokémon Sleep and Asken smartphone apps, each used for at least 7 days to record objective sleep parameters and dietary components, respectively.
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