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Inflammation of a Posterior Ciliary Artery in a Naive Cynomolgus Macaque. | LitMetric

Inflammation of a Posterior Ciliary Artery in a Naive Cynomolgus Macaque.

Toxicol Pathol

Department of Safety Assessment, 7412Genentech Inc, South San Francisco, CA, USA.

Published: April 2021

AI Article Synopsis

Article Abstract

This brief communication describes a previously unreported background lesion in the eye of a naive cynomolgus macaque. Inflammation of a posterior ciliary artery was, in this case, morphologically similar to vascular inflammation of other tissues described in naive cynomolgus macaques. However, the available literature does not describe this lesion at this anatomical site. The affected animal did not present with any abnormal clinical signs and ophthalmological examinations were within normal limits. Toxicologic pathologists should be aware of this finding in order to help differentiate it from a test item-related finding.

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Source
http://dx.doi.org/10.1177/0192623320952337DOI Listing

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