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Primary sclerosing cholangitis in children with inflammatory bowel disease: An ESPGHAN position paper from the Hepatology Committee and the IBD Porto group.
J Pediatr Gastroenterol Nutr
December 2024
Meyer Children's Hospital IRCCS, Florence, Italy.
Objective: We aimed to provide an evidence-supported approach to diagnose, monitor, and treat children with inflammatory bowel disease (IBD) and primary sclerosing cholangitis (PSC).
Methods: The core group formulated seven PICO-structured clinical questions. A systematic literature search from inception to December 2022 was conducted by a medical librarian using MEDLINE and EMBASE.
Macro-vacuolar steatosis in a cirrhotic liver mimicking metastatic disease.
Radiol Case Rep
February 2025
Radiology Unit, "Papardo" Hospital, Messina, ME 98158, Italy.
Multinodular steatosis represents a relatively uncommon manifestation of fatty liver disease (FLD). Co-morbidities such as metabolic syndrome or cirrhosis are often associated. Despite typical features of imaging (ultrasound, CT, and MRI), core biopsy sometimes remains the gold standard for diagnosis.
View Article and Find Full Text PDFExamination of Core Clinical Symptoms of Postoperative Fatigue Syndrome Following Colonoscopy With Sedation.
J Perianesth Nurs
December 2024
Department of Anesthesiology, Northern Jiangsu People's Hospital, Yangzhou, China. Electronic address:
Article Synopsis
- - The study aimed to identify and categorize discomfort symptoms following sedative-administered colonoscopy, with the goal of developing criteria to recognize postoperative fatigue syndrome (POFS).
- - Researchers conducted follow-up interviews with 542 patients who had undergone the procedure to collect data on 19 different discomfort symptoms, including fatigue, lethargy, and dizziness.
- - The key findings suggest that the main symptoms defining POFS are fatigue, lethargy, dizziness, and headache, which should be included in diagnostic criteria for this syndrome.
Identification of immune-associated genes for the diagnosis of ulcerative colitis-associated carcinogenesis via integrated bioinformatics analysis.
Front Oncol
November 2024
Department of Gastroenterology and Hepatology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Background: UC patients suffer more from colorectal cancer (CRC) than the general population, which increases with disease duration. Early colonoscopy is difficult because ulcerative colitis-associated colorectal cancer (UCAC) lesions are flat and multifocal. Our study aimed to identify promising UCAC biomarkers that are complementary endoscopy strategies in the early stages.
View Article and Find Full Text PDFArtificial Intelligence-Assisted Colonoscopy for Polyp Detection : A Systematic Review and Meta-analysis.
Ann Intern Med
December 2024
Section of Digestive Diseases, Clinical and Translational Research Accelerator, and Department of Biomedical Informatics and Data Science, Department of Medicine, Yale School of Medicine, New Haven, Connecticut (D.L.S.).
Article Synopsis
- CADe-enhanced colonoscopy shows significantly higher adenoma detection rates (ADR) and average adenomas per colonoscopy (APC) compared to conventional methods.
- While the detection of advanced colorectal neoplasia (ACN) per colonoscopy was similar between both methods, CADe systems had a higher ACN detection rate (ACN DR).
- The study also found that using CADe led to longer withdrawal times and more non-neoplastic polyps being removed, indicating a trade-off in procedure duration.
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