Background: A majority of bloodstream infections seen in intensive care units stem from intravascular catheters used on patients. Catheter hubs are the entrance for pathogenic microorganisms into the inner surfaces of the catheters. The pathogenic microorganisms colonization in the mentioned areas can cause central line-associated bloodstream infection (CLABSI).
Methods: This study was conducted as a randomized controlled trial to investigate the effect of alcohol-containing caps on the prevention of CLABSI. Total of 95 patients participated in the study. Isopropyl alcohol-containing caps were used for protecting the needle-free connectors closing the hubs of the central venous catheters in the intervention group. However, the control group patient received standard catheter caps.
Result: There was a statistically significant difference between groups in terms of infection distribution (X2 = 13.058; < 0.001). The risk of infection in the control group was 13.7 times higher than the risk of infection in the intervention group.
Discussion: Our results suggest that alcohol-containing caps are effective or in preventing CLABSI.
Conclusion: These findings suggest that alcohol-containing caps on ports are effective in preventing CLABSI.
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http://dx.doi.org/10.1177/1129729820952961 | DOI Listing |
Am J Infect Control
August 2024
PuraCath Medical Inc., Newark, CA. Electronic address:
Background: The standard of care for disinfecting needleless connectors (NCs) of central venous catheters includes alcohol-containing caps or up to a 15-second scrub with alcohol or chlorhexidine. Due to the clinical impact and high cost of treating Central line-associated bloodstream infections (CLABSI), reducing the incidence of CLABSI is a priority for public health and of the Centers for Disease Control. Alcohol-containing caps have been demonstrated to disinfect external NC surfaces, but not the internal surface.
View Article and Find Full Text PDFJ Vasc Access
November 2021
School of Nursing, Maltepe Üniversity, İstanbul, Turkey.
Background: A majority of bloodstream infections seen in intensive care units stem from intravascular catheters used on patients. Catheter hubs are the entrance for pathogenic microorganisms into the inner surfaces of the catheters. The pathogenic microorganisms colonization in the mentioned areas can cause central line-associated bloodstream infection (CLABSI).
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