The "time-varying loudness" (TVL) model of Glasberg and Moore calculates "instantaneous loudness" every 1 ms, and this is used to generate predictions of short-term loudness, the loudness of a short segment of sound, such as a word in a sentence, and of long-term loudness, the loudness of a longer segment of sound, such as a whole sentence. The calculation of instantaneous loudness is computationally intensive and real-time implementation of the TVL model is difficult. To speed up the computation, a deep neural network (DNN) was trained to predict instantaneous loudness using a large database of speech sounds and artificial sounds (tones alone and tones in white or pink noise), with the predictions of the TVL model as a reference (providing the "correct" answer, specifically the loudness level in phons). A multilayer perceptron with three hidden layers was found to be sufficient, with more complex DNN architecture not yielding higher accuracy. After training, the deviations between the predictions of the TVL model and the predictions of the DNN were typically less than 0.5 phons, even for types of sounds that were not used for training (music, rain, animal sounds, and washing machine). The DNN calculates instantaneous loudness over 100 times more quickly than the TVL model. Possible applications of the DNN are discussed.
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http://dx.doi.org/10.1177/2331216520943074 | DOI Listing |
Microvasc Res
January 2025
Department of Ophthalmology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China; Graduate School of Peking Union Medical College, Beijing, China. Electronic address:
Purpose: To evaluate quantitative metrics of neovascularization lesions and choroidal vascular using swept-source optical coherence tomography angiography (SS-OCTA) in polypoidal choroidal vasculopathy (PCV) eyes, and investigate the relationship between imaging biomarkers and treatment outcomes of intravitreal anti-vascular endothelial growth factor (VEGF).
Methods: We retrospectively recruited 56 PCV patients. Choroidal features included subfoveal choroidal thickness (SFCT) and choroidal vascularity index (CVI).
J Clin Med
August 2024
Department of Obstetrics and Gynaecology, Radboud University Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.
Pelvic organ prolapse (POP) affects many women and is often managed with pessary treatment, yet predicting the success of fitting remains challenging. This study aims to identify anatomical parameters associated with successful and unsuccessful pessary treatment using dynamic magnetic resonance imaging (dMRI). A cross-sectional study in Maastricht University Medical Centre (MUMC+), the Netherlands.
View Article and Find Full Text PDFJ Mol Graph Model
November 2024
Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.
Many protein-ionic liquid investigations have examined laccase interactions. Laccases are a class of poly-copper oxidoreductases that retain significant biotechnological relevance owing to their notable oxidative capabilities and their application in the elimination of synthetic dyes, phenolic compounds, insecticides, and various other substances. This study investigates the impact of surface active ionic liquids (SAILs), namely, decyltrimethylammonium bromide [N][Br] and 1-decyl-3-methylimidazolium chloride [C][Cl] as cationic surfactant ionic liquids and cholinium decanoate [Chl][Dec], an anionic surfactant ionic liquid, on the structure and function of laccase from the fungus Trametes versicolor (TvL) by the molecular dynamics (MD) simulation method.
View Article and Find Full Text PDFJ Alzheimers Dis
March 2024
Department of Statistics, University of California, Irvine, CA, USA.
Background: In randomized clinical trials (RCTs), monitoring adverse events (AEs) and serious AEs (SAEs) is critical. All Alzheimer's disease (AD) RCTs require participants to enroll with a study partner.
Objective: We examined AE reporting rates in mild-to-moderate AD trials and their associations with study partner type.
Tissue Eng Part C Methods
March 2024
Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Angiogenesis induced by growth factor administration, which can augment the blood supply in regenerative applications, has drawn wide attention in medical research. Longitudinal monitoring of vascular structure and development is important for understanding and evaluating the dynamics of involved biological processes. In this work, a dual-modality imaging system consisting of photoacoustic microscopy (PAM) and optical coherence tomography (OCT) was applied for noninvasive imaging of angiogenesis in a murine model.
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