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Article Synopsis
  • Geriatric patients (aged 65 and older) present different patterns of rheumatic diseases compared to younger patients, with significantly higher rates of rheumatoid arthritis, polymyalgia rheumatica, crystal arthritis, and osteoarthritis.
  • They also experience more comorbidities such as hypertension, diabetes, and osteoporosis, indicating a greater burden of chronic health issues.
  • Treatment approaches vary, with geriatric patients using more corticosteroids and traditional synthetic treatments but fewer biological treatments, and they have higher mortality rates linked to conditions like cancer and heart disease.
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Article Synopsis
  • A 69-year-old woman with a history of autoimmune conditions was admitted to the emergency department after experiencing fever, malaise, and confusion, which she initially developed while visiting her son in Tennessee, where mold exposure occurred.
  • Laboratory tests confirmed she had both histoplasmosis and coccidioidomycosis, fungal infections that often affect immunocompromised individuals.
  • After treatment with intravenous amphotericin B, her condition improved, allowing her discharge on oral itraconazole with plans for follow-up care.
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Objective: Giant cell arteritis (GCA) is a large-vessel vasculitis that primarily affects elderly individuals. However, data regarding Korean patients with GCA are scarce owing to its extremely low prevalence in East Asia. This study aimed to investigate the clinical characteristics of Korean patients with GCA and their outcomes, focusing on relapse.

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Diagnosing vasculitis with ultrasound: findings and pitfalls.

Ther Adv Musculoskelet Dis

June 2024

Department of Rheumatology and Clinical Immunology, Clinic of Internal Medicine III, University Hospital Bonn, Bonn, Nordrhein-Westfalen, Germany.

Rheumatologists are increasingly utilizing ultrasound for suspected giant cell arteritis (GCA) or Takayasu arteritis (TAK). This enables direct confirmation of a suspected diagnosis within the examination room without further referrals. Rheumatologists can ask additional questions and explain findings to their patients while performing ultrasound, preferably in fast-track clinics to prevent vision loss.

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Modifiable risk factors and inflammation-related proteins in polymyalgia rheumatica: genome-wide meta-analysis and Mendelian randomisation.

Rheumatology (Oxford)

May 2024

Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Nobelsväg 13, 17177, Stockholm, Sweden.

Objective: Polymyalgia rheumatica (PMR) is an age-related inflammatory disease of unknown cause. We aimed to identify potentially modifiable risk factors and therapeutic targets for preventing or treating PMR.

Methods: We meta-analysed genetic association data from 8,156 cases of PMR (defined using diagnostic codes and self-report) and 416,495 controls of European ancestry from the UK Biobank and FinnGen.

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