Objective: To investigate the prevalence, diameter, and position of the alveolar antral artery (AAA) canals and measure the distances from the canal to the maxillary sinus floor and to the edentulous alveolar crest in each posterior maxillary tooth locations by cone beam computed tomography (CBCT).
Methods: CBCT images of the posterior maxillary region from 280 patients were investigated. The prevalence and diameter of the AAA canal were evaluated. The perpendicular distances from the canal to the maxillary sinus floor and to the edentulous alveolar crest of each tooth locations were measured. The mediolateral positions and routes of the canals were observed with novel classification. Statistical analyses were carried out to determine any significant differences in mean distances between the tooth locations along with mean distances of tooth location by age, gender, and dentate status.
Results: The AAA canal was found in 94.6% with a mean diameter ± SD of 1.05 ± 0.34 mm. The mean ± SD perpendicular distance from AAA canal to the edentulous alveolar crest at the first (16.02 ± 3.94 mm) and the second molars (16.74 ± 3.51 mm) were significantly shorter than the second premolar region. The intrasinus mediolateral position of the canal (72.5%) was the most common in concordance with the all-in type mediolateral route (50.9%).
Conclusion: The intrasinus mediolateral position of the AAA canal is a common structure in the lateral wall of maxillary sinus, which could be detected with CBCT images. The all-in type is the most prevalent mediolateral route among a novel 7-type classification system of AAA routes. Owing to the short distance between the AAA canal and the alveolar crest in the first and second molar locations, CBCT images should be taken to investigate the AAA position and route before sinus lift procedure to prevent the risk of hemorrhage.
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http://dx.doi.org/10.1007/s11282-020-00478-3 | DOI Listing |
Surg Radiol Anat
July 2024
Gulhane Faculty of Dentistry, Department of Oral and DentoMaxillofacial Radiology, University of Health Sciences, Ankara, Turkey.
Eur J Cancer
May 2024
Hepato-Gastroenterology Department, Poitiers University Hospital, Poitiers 86000, France. Electronic address:
Background: One randomized phase III trial comparing chemotherapy (CT) with immune checkpoint inhibitors (ICI) has demonstrated significant efficacy of ICI in deficient DNA mismatch repair system/microsatellite instability-high (dMMR/MSI-H) metastatic colorectal cancer. However, few studies have compared ICI with CT in other advanced dMMR/MSI-H digestive tumors.
Methods: In this multicenter study, we included patients with advanced dMMR/MSI-H non-colorectal digestive tumors treated with chemotherapy and/or ICIs.
BMC Med Genomics
January 2024
Genetics Unit, Histology Department, Faculty of Medicine, Suez Canal University, 41522, Ismailia, Egypt.
Background: Variation in host immune responses to SARS-CoV-2 is regulated by multiple genes involved in innate viral response and cytokine storm emergence like IL-10 and TNFa gene polymorphisms. We hypothesize that IL-10; -592 C > A and - 1082 A > G and TNFa-308 G > A are associated with the risk of SARS-COV2 infections and clinical outcome.
Methods: Genotyping, laboratory and radiological investigations were done to 110 COVID-19 patients and 110 healthy subjects, in Ismailia, Egypt.
Br J Cancer
February 2024
Department of Digestive Oncology, Georges Pompidou European Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP), Université Paris Cité, Paris, France.
Background: The outstanding efficacy of immunotherapy in metastatic dMMR/MSI gastro-intestinal (GI) cancers has led to a rapid increase in the number of patients treated. However, 20-30% of patients experience primary resistance to immune checkpoint inhibitors (ICIPR) and need better characterization.
Methods: This AGEO real-world study retrospectively analyzed the efficacy and safety of ICIs and identified clinical variables associated with ICIPR in patients with metastatic dMMR/MSI GI cancers treated with immunotherapy between 2015 and 2022.
Front Oncol
November 2023
Institut du Cancer de Montpellier, Department of Radiation Oncology, Montpellier, France.
Purpose/objectives: An artificial intelligence-based pseudo-CT from low-field MR images is proposed and clinically evaluated to unlock the full potential of MRI-guided adaptive radiotherapy for pelvic cancer care.
Materials And Method: In collaboration with TheraPanacea (TheraPanacea, Paris, France) a pseudo-CT AI-model was generated using end-to-end ensembled self-supervised GANs endowed with cycle consistency using data from 350 pairs of weakly aligned data of pelvis planning CTs and TrueFisp-(0.35T)MRIs.
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