Two new milbemycin metabolites, 13-hydroxymilbemycin () and 26-methyl-13-hydroxymilbemycin (), were isolated from the fermentation broth of a genetically engineered strain AVE-H39. Their structures were determined by the comprehensive spectroscopic data, including 1 D, 2 D NMR, MS spectral analysis and the comparison with data from the literature. Compounds and not only exhibited potent acaricidal activities against , but also had nematocidal activity against .
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| http://dx.doi.org/10.1080/10286020.2020.1803294 | DOI Listing |
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