AI Article Synopsis

  • Cystic lymphatic malformations are due to abnormal development of lymphatic structures during embryonic growth.
  • A case study discusses a preterm baby born at 34 weeks with a large cystic lymphatic malformation in her neck, causing breathing issues.
  • The baby was treated with sirolimus, an mTOR inhibitor, alongside sclerotherapy, showing that early treatment can be safe and effective for such conditions.

Article Abstract

Cystic lymphatic malformations result from an abnormal embryological development of the lymphatic structures. Here we report on a case of a preterm female baby, born at 34 weeks of gestation, with a voluminous cervicofacial cystic lymphatic malformation responsible for an airway obstruction. An mTOR inhibitor, sirolimus, was started from the first day of life, and was combined with iterative sclerotherapy procedures. This case illustrates a safe and successful early administration of sirolimus in a preterm neonate.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399047PMC
http://dx.doi.org/10.3389/fped.2020.00418DOI Listing

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