In the field of brain-computer interface (BCI), selecting efficient and robust features is very seductive for artificial intelligence (AI)-assisted clinical diagnosis. In this study, based on an embedded feature selection model, we construct a stacked deep structure for feature selection in a layer-by-layer manner. Its promising performance is guaranteed by the stacked generalized principle that random projections added into the original features can help us to continuously open the manifold structure existing in the original feature space in a stacked way. With such benefits, the original input feature space becomes more linearly separable. We use the epilepsy EEG data provided by the University of Bonn to evaluate our model. Based on the EEG data, we construct three classification tasks. On each task, we use different feature selection models to select features and then use two classifiers to perform classification based on the selected features. Our experimental results show that features selected by our new structure are more meaningful and helpful to the classifier hence generates better performance than benchmarking models.
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http://dx.doi.org/10.3389/fnins.2020.00829 | DOI Listing |
Sci Prog
January 2025
Department of Environmental and Industrial Biotechnology, Institute of Biotechnology, University of Gondar, Gondar, Ethiopia.
Objective: Heavy metal pollution is one of the more recent problems of environmental degradation caused by rapid industrialization and human activity. The objective of this study was to isolate, screen, and characterize heavy metal-resistant bacteria from solid waste disposal sites.
Methods: In this study, a total of 18 soil samples were randomly selected from mechanical sites, metal workshops, and agricultural land that received wastewater irrigation.
Comput Methods Biomech Biomed Engin
January 2025
Department of Electronics and Electrical Communications, Faculty of Electronic Engineering, Menoufia University, Menouf, Egypt.
The conversion of a person's intentions into device commands through the use of brain-computer interface (BCI) is a feasible communication method for individuals with nervous system disorders. While common spatial pattern (CSP) is commonly used for feature extraction in BCIs, it has limitations. It is known for its susceptibility to noise and tendency to overfit.
View Article and Find Full Text PDFCureus
December 2024
Internal Medicine, University of Alexandria, Alexandria, EGY.
Aim: Thyroid nodules, based on high-resolution ultrasonography (HRUS), are among the most common endocrine abnormalities that affect the general population because of their high estimated prevalence rates. Fine needle aspiration cytology (FNAC) is a safe, cost-effective modality to differentiate between benign and malignant thyroid nodules based on the Bethesda System for Reporting Thyroid Cytopathology (BSRTC), thus avoiding unnecessary surgery. However, categories III and IV of BSRTC remain a controversial issue in clinical practice, encompassing a wide range of risks of malignancy.
View Article and Find Full Text PDFJACS Au
January 2025
Department of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.
Polyketide synthases (PKSs) are multidomain enzymatic assembly lines that biosynthesize a wide selection of bioactive natural products from simple building blocks. In contrast to their -acyltransferase (AT) counterparts, -AT PKSs rely on stand-alone ATs to load extender units onto acyl carrier protein (ACP) domains embedded in the core PKS machinery. -AT PKS gene clusters also encode stand-alone acyl hydrolases (AHs), which are predicted to share the overall fold of ATs but function like type II thioesterases (TEs), hydrolyzing aberrant acyl chains from ACP domains to promote biosynthetic efficiency.
View Article and Find Full Text PDFChem Biomed Imaging
January 2025
Precision Healthcare University Research Institute, Queen Mary University of London, Whitechapel, London E1 4NS, United Kingdom.
Bacterial resistance, primarily stemming from misdiagnosis, misuse, and overuse of antibacterial medications in humans and animals, is a pressing issue. To address this, we focused on developing a fluorescent probe for the detection of bacteria, with a unique feature-an exceptionally long fluorescence lifetime, to overcome autofluorescence limitations in biological samples. The polymyxin-based probe (ADOTA-PMX) selectively targets Gram-negative bacteria and used the red-emitting fluorophore azadioxatriangulenium (with a reported fluorescence lifetime of 19.
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