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Nanobiochar paper based electrochemical immunosensor for fast and ultrasensitive detection of microcystin-LR. | LitMetric

Nanobiochar paper based electrochemical immunosensor for fast and ultrasensitive detection of microcystin-LR.

Sci Total Environ

Key Laboratory of Groundwater Resources and Environment (Jilin University), Ministry of Education, Jilin Provincial Key Laboratory of Water Resources and Environment, Jilin University, Changchun 130021, China. Electronic address:

Published: January 2021

AI Article Synopsis

  • A new, affordable electrochemical immunosensor using conductive nanobiochar paper was developed for quick detection of microcystin-LR (MCLR) toxin in water.
  • The sensor works by coating filter paper with nanobiochar particles and anti-MCLR antibodies, allowing for specific measurements in under 5 minutes, with a detection limit of 17 pM.
  • The immunosensor demonstrated strong selectivity, reproducibility, and stability, making it suitable for environmental monitoring and indicating potential for cost-effective electrochemical devices.

Article Abstract

A portable, cheap and sensitive paper type electrochemical immunosensor was developed with conductive nanobiochar paper as the conductive layer and utilized for sensitive detection of microcystin-LR (MCLR) toxin in water. The paper immunosensor was constructed by coating of highly conductive and dispersible nanobiochar particle (nBC) and anti-MCLR antibody on the filter paper via dipping-drying method. The presence of MCLR could be specifically quantified amperometrically by the nBC-paper immunosensor with the response time of less than 5 min, and the lowest detection limit of 17 pM (0.017 μg/L) was achieved. Moreover, the proposed immunosensor exhibited high selectivity, reproducibility and storage stability, and was also used for environmental water detection with satisfactory recovery. The successful fabrication of low cost and ubiquitous biochar based paper type electrochemical immunosensing system would have significant value for the development of highly cost-effective electrochemical device.

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Source
http://dx.doi.org/10.1016/j.scitotenv.2020.141692DOI Listing

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