AI Article Synopsis
- A multicentric study in Paris analyzed characteristics and outcomes of 821 hospitalized patients aged 70 and older with confirmed COVID-19 from March to April 2020.
- Patients had a mean age of 86, with 85% having two or more pre-existing health conditions, and exhibiting common symptoms such as asthenia, fever, and dyspnea.
- The in-hospital mortality rate was 31%, with factors like male gender, lower functional status, and specific health anomalies increasing the likelihood of death, highlighting the importance of early risk assessment for older patients.
Article Abstract
Background: There is limited information describing the characteristics and outcomes of hospitalized older patients with confirmed coronavirus disease 2019 (COVID-19).
Method: We conducted a multicentric retrospective cohort study in 13 acute COVID-19 geriatric wards, from March 13 to April 15, 2020, in Paris area. All consecutive patients aged 70 years and older, with confirmed COVID-19, were enrolled.
Results: Of the 821 patients included in the study, the mean (SD) age was 86 (7) years; 58% were female; 85% had ≥2 comorbidities; 29% lived in an institution; and the median [interquartile range] Activities of Daily Living scale (ADL) score was 4 [2-6]. The most common symptoms at COVID-19 onset were asthenia (63%), fever (55%), dyspnea (45%), dry cough (45%), and delirium (25%). The in-hospital mortality was 31% (95% confidence interval [CI] 27-33). On multivariate analysis, at COVID-19 onset, the probability of in-hospital mortality was increased with male gender (odds ratio [OR] 1.85; 95% CI 1.30-2.63), ADL score <4 (OR 1.84; 95% CI 1.25-2.70), asthenia (OR 1.59; 95% CI 1.08-2.32), quick Sequential Organ Failure Assessment score ≥2 (OR 2.63; 95% CI 1.64-4.22), and specific COVID-19 anomalies on chest computerized tomography (OR 2.60; 95% CI 1.07-6.46).
Conclusions: This study provides new information about older patients with COVID-19 who are hospitalized. A quick bedside evaluation at admission of sex, functional status, systolic arterial pressure, consciousness, respiratory rate, and asthenia can identify older patients at risk of unfavorable outcomes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546043 | PMC |
| http://dx.doi.org/10.1093/gerona/glaa210 | DOI Listing |
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