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Risk Factors for Mortality Among Older Adults with Hospital-Acquired Bloodstream Infections in the Intensive Care Unit: A Multicenter Cohort Study.
Infect Dis Ther
January 2025
Infectious Diseases Unit, Sheba Medical Center, Ramat-Gan, Israel.
Introduction: We aimed to investigate risk factors for mortality among older adults (≥ 75 years) with hospital-acquired bloodstream infections (HA-BSI) in the intensive care unit (ICU).
Methods: We included patients aged ≥ 75 years with HA-BSI in ICU from the EUROBACT-2 cohort (2019-2021). Univariable and multivariable analyses were conducted to identify predictors of 28-day mortality.
Background: Coronavirus disease 2019 resulted in restrictions in didactic and clinical rotations while sites denied entry or limited numbers of nursing student placements to decrease impact staff nurse workload. Pandemic incidences of hospital-acquired infections, central line-associated bloodstream infections (CLABSIs), and catheter-associated urinary tract infections (CAUTIs) increased, underscoring the importance of increasing workforce-ready nurses.
Method: To increase the number of nursing students permitted into the hospital, hospital and school administrators devised the nurse assist program (NAP), which is a collaborative approach developed to address increased staff workloads and personnel shortages and facilitate student return to clinical settings.
Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis.
J Vis Exp
December 2024
Integrated Chinese and Western Medicine Ear, Nose, Throat, Head, and Neck Surgery, Hospital of Chengdu University of Traditional Chinese Medicine;
Acupuncture Point Embedding Therapy is a comprehensive treatment method that combines modern biomaterials with acupuncture techniques. Acupoint catgut embedding (ACE) not only avoids the adverse reactions associated with Western medicine but also incorporates the benefits of traditional acupuncture, extending the duration of its therapeutic effects. Allergic rhinitis (AR) is a condition known for its challenging treatment and tendency to persist.
View Article and Find Full Text PDFThe financial burden of healthcare-associated infections: a propensity score analysis in an Italian healthcare setting.
Infect Prev Pract
March 2025
Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
Article Synopsis
- Hospital-acquired infections (HAIs) pose a major global health issue, increasing patient safety risks and causing significant financial strain on healthcare systems.
- A study conducted in Rome analyzed data from over 12,000 hospital patients to assess how HAIs affected hospital costs, revealing a 53.4% increase in average costs for infected patients compared to those without infections.
- The findings underscore the necessity for targeted prevention strategies, as specific types of infections and microbes contribute to higher healthcare expenses, ultimately calling for improved efforts to minimize HAIs in hospitals.
Aerosolized plus intravenous polymyxin B in comparison to intravenous polymyxin B alone for the management of HAP caused by carbapenem-resistant gram-negative bacteria: a prospective multicenter cohort study.
Int J Antimicrob Agents
December 2024
Department of Critical Care Medicine, the Second Affiliated Hospital of Xi'an Jiaotong University, China. Electronic address:
Objectives: This study aimed to evaluate the clinical effectiveness of combined aerosolized (AER) and intravenous (IV) polymyxin B in managing patients with hospital-acquired pneumonia (HAP) caused by carbapenem-resistant gram-negative organism (CRO) .
Methods: This multicenter prospective cohort study was conducted across six intensive care units in municipal and above-municipal hospitals in Shaanxi, China, from January 1, 2021 to December 31, 2022. Patients with CRO pneumonia were categorized into the intravenous group (IV polymyxin B alone) and the combination group (AER plus IV polymyxin B).
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