RETRACTED: miR-1290 promotes proliferation and suppresses apoptosis in acute myeloid leukemia by targeting FOXG1/SOCS3.

J Biol Regul Homeost Agents

Department of Pediatrics, Taian City Central Hospital, Taian, Shandong Province, China.

Published: September 2020

Retraction statement. We, the Editors and Publisher of Journal of Biological Regulators and Homeostatic Agents, have retracted the following article: "miR-1290 promotes proliferation and suppresses apoptosis in acute myeloid leukemia by targeting FOXG1/SOCS3". Published in our Vol. 33 n. 6, 2019 issue, DOI: 10.23812/19-189-A. The article has been retracted following receipt of information from the corresponding author X.L. Ju, informing us that "they found that the cell lines they had been experimenting with were contaminated, and some of the results could not be repeated. In order not to mislead readers, they have withdrawn this manuscript with apologies". The article is withdrawn from all print and electronic editions.We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines on retractions.The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as "Retracted."

Download full-text PDF

Source
http://dx.doi.org/10.23812/19-189-ARDOI Listing

Publication Analysis

Top Keywords

promotes proliferation
8
proliferation suppresses
8
suppresses apoptosis
8
apoptosis acute
8
acute myeloid
8
myeloid leukemia
8
leukemia targeting
8
retracted article
8
retracted
4
retracted mir-1290
4

Similar Publications

Inhibition of DEK restores hematopoietic stem cell function in Fanconi anemia.

J Exp Med

March 2025

Department of Hematology, The Second Affiliated Hospital of Chongqing Medical University, School of Basic Medical Sciences, Chongqing Medical University, Chongqing, China.

Hematopoietic stem cells (HSCs) are susceptible to replication stress, which is a major contributor to HSC defects in Fanconi anemia (FA). Here, we report that HSCs relax the global chromatin by downregulating the expression of a chromatin architectural protein, DEK, in response to replication stress. DEK is abnormally accumulated in bone marrow (BM) CD34+ cells from patients with FA and in Fancd2-deficient HSCs.

View Article and Find Full Text PDF

Bone defects are difficult to treat clinically and most often require bone grafting for repair. However, the source of autograft bone is limited, and allograft bone carries the risk of disease transmission and immune rejection. As tissue engineering technology advances, bone replacement materials are playing an increasingly important role in the treatment of bone defects.

View Article and Find Full Text PDF

Colorectal cancer (CRC) is one of the most common malignancies. Hypoxia can promote the occurrence and development of CRC. However, how hypoxia regulates the CRC immune microenvironment needs to be further explored.

View Article and Find Full Text PDF

Cell proliferation suppressor RBR1 interacts with ARID1 to promote pollen mitosis via stabilizing DUO1 in Arabidopsis.

New Phytol

January 2025

State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, 200438, China.

In plants, sperm cell formation involves two rounds of pollen mitoses, in which the microspore initiates the first pollen mitosis (PMI) to produce a vegetative cell and a generative cell, then the generative cell continues the second mitosis (PMII) to produce two sperm cells. DUO1, a R2R3 Myb transcription factor, is activated in the generative cell to promote S-G2/M transition during PMII. Loss-of-function of DUO1 caused a complete arrest of PMII.

View Article and Find Full Text PDF

Purpose: Previous studies have shown that long non-coding RNA GUSBP11 is abnormally expressed in patients with periodontitis, but the specific mechanism remains to be investigated. The purpose of this study was to explore the role of GUSBP11/miR-185-5p in chronic periodontitis (CP) and its potential mechanism, so as to provide a basis for elucidating the pathogenesis of CP.

Patients And Methods: The expression trends of GUSBP11 and miR-185-5p in gingival crevicular fluid of CP patients and control group were analyzed by RT-qPCR.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!