In many countries, the lock-down due to the COVID-19 pandemic triggered discussions on the use of digital interaction formats for academic exchange. The pace with which researchers adopted digital formats for conferences, lectures, and meetings revealed that currently available tools can substitute many of the physical interactions in the workplace. It also showed that academics are willing to use digital tools for scientific exchange. This article sheds light on scholars' experiences with digital formats and tools during the pandemic. We argue that digital interaction formats increase the inclusivity of knowledge exchange, reduce time and costs of organizing academic interactions, and enable more diverse workspaces with geographical and temporal flexibility. However, we also observe that digital interaction formats struggle to reproduce social interactions such as informal discussions, raise new concerns on data security, and can induce higher stress levels due to the blurring of the boundaries between work and private spaces. We argue that digital formats are not meant to substitute physical interactions entirely, but rather reshape how research communities operate and how academics socialize. We expect hybrid formats to emerge, which combine digital and physical interaction formats, and an increase in digital interactions between geographically distant working groups. We conclude that the time has come for digital interaction formats to be part of a new regime in the field of academic exchange.
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http://dx.doi.org/10.1016/j.erss.2020.101684 | DOI Listing |
J Control Release
January 2025
Biotherapeutic Engineering and Drug Targeting, Department of Health Technology, Technical University of Denmark (DTU), Kgs. Lyngby, Denmark. Electronic address:
Despite three decades of intense research, active targeting of liposomes have not been successfully achieved in a clinical setting. A potential explanation is that the clinically used liposomes lose their targeting abilities upon circulation. Here, we investigated if DSPE-PEG anchored antibody-based targeting ligands dissociate from clinically relevant drug delivery liposomes during circulation in mice.
View Article and Find Full Text PDFAnal Chem
January 2025
School of Chemistry and Chemical Engineering, State Key Laboratory of Digital Medical Engineering, Southeast University, Nanjing 211189, China.
PIWI-interacting RNAs (piRNAs) are a class of small noncoding RNAs associated with PIWI proteins within the male germline, and they play significant roles in maintaining genome stability via the modulation of gene expression. The piRNAs are implicated in the progression of various cancers, but the simultaneous monitoring of multiple piRNAs remains a challenge. Herein, we construct a single-molecule biosensor based on polymerization-transcription-mediated target regeneration for the simultaneous one-pot detection of multiple piRNAs.
View Article and Find Full Text PDFData Brief
February 2025
Department of Computer Science, FEL, Czech Technical University in Prague, Technická 2, Prague 126 627, Czech Republic.
This data article introduces a new network dataset created to help understand how geographical location impacts the quality, type, and amount of incoming network attacks received by honeypots. The dataset consists of 12.4 million network flows collected from nine low-interaction honeypots in nine cities across the world for 65 days, from April 29th to July 1st, 2024.
View Article and Find Full Text PDFHollow-core optical fiber (HCF) gas cells are an attractive option for many applications including metrology and non-linear optics due to the enhanced gas-light interaction length in a compact and lightweight format. Here, we report the first demonstration and characterization of a selectively pressurized, hermetically sealed hollow-core fiber-based gas cell, where the core is filled with a higher gas pressure than the cladding to enhance the optical performance. This differential gas pressure creates a gas-induced differential refractive index (GDRI) that is shown to enable significant modification of the HCF's optical performance.
View Article and Find Full Text PDFBMC Bioinformatics
January 2025
Biology Department, University of Massachusetts Amherst, Amherst, MA, USA.
Background: High-throughput behavioral analysis is important for drug discovery, toxicological studies, and the modeling of neurological disorders such as autism and epilepsy. Zebrafish embryos and larvae are ideal for such applications because they are spawned in large clutches, develop rapidly, feature a relatively simple nervous system, and have orthologs to many human disease genes. However, existing software for video-based behavioral analysis can be incompatible with recordings that contain dynamic backgrounds or foreign objects, lack support for multiwell formats, require expensive hardware, and/or demand considerable programming expertise.
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