Not just antibodies: B cells and T cells mediate immunity to COVID-19.

Nat Rev Immunol

Broeglemann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway.

Published: October 2020

Recent reports that antibodies to SARS-CoV-2 are not maintained in the serum following recovery from the virus have caused alarm. However, the absence of specific antibodies in the serum does not necessarily mean an absence of immune memory. Here, we discuss our current understanding of the relative contribution of B cells and T cells to immunity to SARS-CoV-2 and the implications for the development of effective treatments and vaccines for COVID-19.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443809PMC
http://dx.doi.org/10.1038/s41577-020-00436-4DOI Listing

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