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Aerobic exercise regulates gut microbiota profiles and metabolite in the early stage of Alzheimer's disease.
FASEB J
January 2025
Department of Neurology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Aerobic exercise (AE) has been shown to offer significant benefits for Alzheimer's disease (AD), potentially influencing the gut microbiota. However, the impact of changes in intestinal flora in early Alzheimer's disease induced by aerobic exercise on metabolic pathways and metabolites is not well understood. In this study, 3-month-old APP/PS1 and C57BL/6 mice were divided into two groups each: a control group (ADC for APP/PS1 and WTC for C57BL/6) and an aerobic exercise group (ADE for APP/PS1 and WTE for C57BL/6).
View Article and Find Full Text PDFCurrent status of pulmonary rehabilitation and impact on prognosis of patients with idiopathic pulmonary fibrosis in South Korea.
J Thorac Dis
December 2024
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Background: The benefits of pulmonary rehabilitation (PR) for patients with idiopathic pulmonary fibrosis (IPF) have been limited to improving dyspnea, exercise capacity, and quality of life (QoL). This study aimed to assess the current status of PR and its effect on prognosis.
Methods: The Nationwide Korean Health Insurance Review and Assessment Service (HIRA) database was used in this study.
Meta-analyses of the effects of high-intensity interval training in elite athletes-part I: mean effects on various performance measures.
Front Physiol
January 2025
Internet Society for Sport Science, Auckland, New Zealand.
Introduction: Meta-analysts have found that high-intensity interval training (HIIT) improves physical performance, but limited evidence exists regarding its effects on highly trained athletes, measures beyond maximum oxygen uptake ( O), and the moderating effects of different types of HIIT. In this study, we present meta-analyses of the effects of HIIT focusing on these deficits.
Methods: The effects of 6 types of HIIT and other moderators were derived from 34 studies involving highly trained endurance and elite athletes in percent units via log-transformation from separate meta-regression mixed models for sprint, time-trial, aerobic/anaerobic threshold, peak speed/power, repeated-sprint ability, O, and exercise economy.
Comparative analysis of land-based vs. water-based balance training on quality of life and physical and psychological deficits in athletes with chronic ankle instability: a randomized controlled trial.
BMC Sports Sci Med Rehabil
January 2025
Department of Sport Science, University College of Omran and Tosseeh, Hamadan, Iran.
Background: Aquatic training is known for its effective and gentle rehabilitation benefits, but its impact on athletes with chronic ankle instability (CAI) remains underexplored. This study compares the effects of water-based and land-based balance training on functional performance, dynamic balance, fear of reinjury, and quality of life in athletes with CAI.
Methods: Forty-one athletes with chronic ankle instability (CAI) were randomly assigned to water-based (WBBE, n = 21) or land-based (LBBE, n = 20) balance exercise groups, completing 24 sessions of 30-45 min over 8 weeks.
The effect of the APOE4 genotype on physiological and cognitive health in randomised controlled trials with an exercise intervention: a systematic review and meta-analysis.
Trials
January 2025
School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
Background: Alzheimer's disease is caused by modifiable and non-modifiable risk factors. Randomised controlled trials have investigated whether the strongest genetic risk factor for Alzheimer's disease, APOE4, impacts the effectiveness of exercise on health. Systematic reviews are yet to evaluate the effect of exercise on physical and cognitive outcomes in APOE genotyped participants.
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