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| http://dx.doi.org/10.1016/j.tifs.2020.07.006 | DOI Listing |
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Gut microbiome-gut brain axis-depression: interconnection.
World J Biol Psychiatry
December 2024
Institute of Biosciences and Technology, MGM University, Aurangabad, India.
Objectives: The relationship between the gut microbiome and mental health, particularly depression, has gained significant attention. This review explores the connection between microbial metabolites, dysbiosis, and depression. The gut microbiome, comprising diverse microorganisms, maintains physiological balance and influences health through the gut-brain axis, a communication pathway between the gut and the central nervous system.
View Article and Find Full Text PDFDeciphering the role of probiotics in mental health: a systematic literature review of psychobiotics.
Benef Microbes
November 2024
Third World Center for Science and Technology, HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, 63597University of Karachi, Karachi 75270, Pakistan.
Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit to the host. The selection criteria for probiotics include strain safety, viability, tolerance, metabolite production and/or the ability to modulate the immune system. Probiotics are commonly used in industries, such as food, agriculture, medicine, biotechnology, pharmaceuticals, and aquaculture.
View Article and Find Full Text PDFBifidobacteria with indole-3-lactic acid-producing capacity exhibit psychobiotic potential via reducing neuroinflammation.
Cell Rep Med
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State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China. Electronic address:
The escalating global prevalence of depression demands effective therapeutic strategies, with psychobiotics emerging as a promising solution. However, the molecular mechanisms governing the neurobehavioral impact of psychobiotics remain elusive. This study reveals a significant reduction in hippocampal indole-3-lactic acid (ILA) levels in depressed mice, which is ameliorated by the psychobiotic Bifidobacterium breve.
View Article and Find Full Text PDFFibre & fermented foods: differential effects on the microbiota-gut-brain axis.
Proc Nutr Soc
October 2024
APC Microbiome Ireland, University College Cork, Cork, Ireland.
The ability to manipulate brain function through the communication between the microorganisms in the gastrointestinal tract and the brain along the gut-brain axis has emerged as a potential option to improve cognitive and emotional health. Dietary composition and patterns have demonstrated a robust capacity to modulate the microbiota-gut-brain axis. With their potential to possess pre-, pro-, post-, and synbiotic properties, dietary fibre and fermented foods stand out as potent shapers of the gut microbiota and subsequent signalling to the brain.
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