The toxic smoke production of four rainscreen façade systems were compared during large-scale fire performance testing on a reduced height BS 8414 test wall. Systems comprising 'non-combustible' aluminium composite material (ACM) with polyisocyanurate (PIR), phenolic foam (PF) and stone wool (SW) insulation, and polyethylene-filled ACM with PIR insulation were tested. Smoke toxicity was measured by sampling gases at two points - the exhaust duct of the main test room and an additional 'kitchen vent', which connects the rainscreen cavity to an occupied area. Although the toxicity of the smoke was similar for the three insulation products with non-combustible ACM, the toxicity of the smoke flowing from the burning cavity through the kitchen vent was greater by factors of 40 and 17 for PIR and PF insulation respectively, when compared to SW. Occupants sheltering in a room connected to the vent are predicted to collapse, and then inhale a lethal concentration of asphyxiant gases. This is the first report quantifying fire conditions within the cavity and assessing smoke toxicity within a rainscreen façade cavity.
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http://dx.doi.org/10.1016/j.jhazmat.2020.123694 | DOI Listing |
BMC Pharmacol Toxicol
January 2025
Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, 9713643138, Iran.
Background: Cerebrovascular accidents are known as a great cause of morbidity and mortality worldwide. Although there are known risk factors for ischemic stroke, the cases that cannot be justified with these risk factors are increasing. Toxic metals as a potential risk factor for other diseases in humans are assessed in this study in the CVA group and compared to controls.
View Article and Find Full Text PDFJ Occup Environ Med
January 2025
From the Centre for Fire and Hazards Sciences, University of Central Lancashire, Preston, Lancashire, United Kingdom.
Objective: This study assesses the health symptoms and longer-term health outcomes of firefighters who attended the Grenfell Tower fire.
Methods: All available data sources were analyzed, including databases published by the Public Inquiry, the Firefighter Cancer and Disease Registry, incident logs, and sickness reports up to 3 years postfire.
Results: More than three times as many firefighters who reported exposure to smoke during the fire also reported digestive and respiratory diseases following the fire, compared with those not reporting exposure to smoke.
Nanotheranostics
January 2025
Department of Research and Innovation, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai - 602105, Tamil Nadu, India.
In an era where chemical synthesis of nanomaterial is accounting for the generation of toxic wastes, leading to nanotoxicity, the present work focuses on the extraction of carbon nanodots from available natural sources such as turmeric smoke. The extracted carbon nanodots were characterized and their physical and chemical attributes were confirmed. The antibacterial property of the isolated carbon nanodots was tested against coliforms and oral bacteria.
View Article and Find Full Text PDFSci Rep
December 2024
Division of Pulmonary and Critical Care, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095-1690, USA.
Electronic cigarettes (e-cigs) fundamentally differ from tobacco cigarettes in their generation of liquid-based aerosols. Investigating how e-cig aerosols behave when inhaled into the dynamic environment of the lung is important for understanding vaping-related exposure and toxicity. A ventilated artificial lung model was developed to replicate the ventilatory and environmental features of the human lung and study their impact on the characteristics of inhaled e-cig aerosols from simulated vaping scenarios.
View Article and Find Full Text PDFFood Chem Toxicol
December 2024
Departments of Otolaryngology-Head and Neck Surgery; Departments of Cell Biology, The University of Oklahoma Health Sciences Center, Oklahoma City OK 73104, USA; Departments of TSET Health Promotion Research Center, Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA. Electronic address:
Electronic cigarettes (e-cigarettes) have emerged as a potential alternative to traditional smoking and may aid in tobacco harm reduction and smoking cessation. E-cigarette use has notably increased, especially among young non-tobacco users, raising concerns due to the unknown long-term health effects. The oral cavity is the first and one of the most crucial anatomical sites for the deposition of e-cigarette aerosols.
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