Large Congenital Facial Teratoma Associated With Neurological Migration Disorder (Polymicrogyria) and Absent Corpus Callosum.

J Craniofac Surg

Plastic and Reconstructive Surgery Department, Leeds General Infirmary, Leeds, UK.

Published: June 2021

AI Article Synopsis

  • The author discusses a severe case of a facial germ line tumor linked to neurological disorders that hasn't been documented before.
  • A 33-year-old woman had a significant facial mass, and after surgical removal, it turned out to be a grade 3 immature teratoma.
  • Unfortunately, the tumor recurred shortly after surgery, and the patient ultimately died from complications, highlighting the complexity and poor outlook of such conditions.

Article Abstract

Background: Herein, the author report a severe case of large facial mixed germ line tumor associated with neuronal migration disorder, polymicrogyria, and corpus callosum agenesis. This specific association has not been reported as yet.

Method: A 33-year-old primiparous woman at 38th week, delivered 3820 g male baby, via Cesarian section. Postpartum profuse bleeding was noticed from a large, ulcerative, 7 cm exophytic left facial mass, which was controlled nonoperatively. The treatment included surgical excision and 560 g of large facial tumor. Histology results revealed mixed germ line tumor with grade 3, immature teratoma.

Results: Four months postoperatively the teratoma recurred in the buccal, tonsillar, and parapharyngeal areas. Fourteen months following the initial surgical excision the patient died from airway obstruction.

Conclusion: Due to poor initial prognosis further treatment of the facial malignancy was not feasible. However, initial, early postnatal, excisional surgery provided a prolonged and better quality of life for the patient and family.

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Source
http://dx.doi.org/10.1097/SCS.0000000000006879DOI Listing

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