Non-ossifying fibroma (NOF) is a common benign bone tumor with a high probability of occurrence in children and adolescents. It is commonly seen in the metaphysis of long bones, eccentrically located, and can coexist with other malignant tumors such as neuroendocrine tumors (NET). To date, plain radiographs play a major role in the diagnosis of these benign bone tumors. Herein, we report the case of a 13-year-old male patient who was diagnosed with pulmonary NET and underwent right lung lobectomy for a hilar mass which later revealed a well-differentiated NET. The follow-up Ga DOTA-TOC PET/CT showed a focal somatostatin receptor expression in the left distal femur, with corresponding CT component findings of a well-defined osteolytic bone lesion located within the medial aspect of the left distal femoral metaphysis, strongly indicative of NOF. To the best of our knowledge, this is the first reported case of such an occurrence.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429592 | PMC |
http://dx.doi.org/10.1007/s13139-020-00650-x | DOI Listing |
Am J Sports Med
January 2025
University of Alabama at Birmingham, Birmingham, Alabama, USA.
Background: Benign bone lesions are a common incidental finding in athletes during workup for musculoskeletal complaints, and athletes are frequently advised to halt participation in contact sports. There are no current guidelines to assist clinicians in referring patients with these lesions to a subspecialist or in advising athletes on the safety of returning to sport.
Purpose: To assist sports medicine physicians in appropriate referral for patients with benign bone lesions through presentation of a literature review and the case of an adolescent athlete with a benign bone lesion in a location with a significant fracture risk.
Cureus
November 2024
Orthopedic Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, IND.
Non-ossifying fibroma (NOF) is a benign expansive lytic lesion more frequently found in children and adolescents at the metaphysis of long bones in and around the knee joint, typically resolving spontaneously or by ossification. This report presents a rare case of an 11-year-old child with a pathological subtrochanteric femur fracture attributed to an underlying NOF. We describe the diagnosis and surgical management of curettage and internal fixation using a proximal humerus locking plate, resulting in complete resorption of the lytic zone and an excellent clinical outcome.
View Article and Find Full Text PDFJ Clin Med
September 2024
Department of Physical Medicine and Rehabilitation, Malatya Turgut Ozal University, 44210 Malatya, Turkey.
Fibrous cortical defect (FCD) and non-ossifying fibroma (NOF) are incidentally recognised and benign developmental lesions. The objective of this study was to ascertain the clinical manifestations and symptoms of FCDs/NOFs in children and adolescent patients, to characterise the lesions radiologically using X-ray and MRI techniques, and to determine the relationship between physical activity and the condition. The study included patients under the age of 18 with radiological lesions on their extremities.
View Article and Find Full Text PDFEur Radiol
September 2024
Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Objective: First, to determine the frequency and spectrum of osteoid osteoma (OO)-mimicking lesions among presumed OO referred for radiofrequency ablation (RFA). Second, to compare patient sex and age, lesion location, and rates of primary treatment failure for OO based on histopathology results.
Materials And Methods: A retrospective review was performed of all first-time combined CT-guided biopsy/RFA for presumed OO at a single academic center between January 1990 and August 2023.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!