AI Article Synopsis
- - This study aimed to create a detailed cardiovascular magnetic resonance (CMR) method for grading diastolic dysfunction (DD) and to compare its accuracy against traditional echocardiography.
- - Involving 46 patients, the research measured various CMR parameters like diastolic velocities and left atrial volume, using advanced imaging techniques to evaluate DD.
- - The results indicated a high agreement (93%) between CMR and echocardiography for DD grading, with a strong correlation noted, suggesting CMR is a reliable tool for diagnosing DD.
Article Abstract
Objectives: The aims of this study were to develop a comprehensive cardiovascular magnetic resonance (CMR) approach to diastolic dysfunction (DD) grading and to evaluate the accuracy of CMR in the diagnosis of DD compared with echocardiography.
Background: Left ventricular DD is routinely assessed using echocardiography.
Methods: Consecutive clinically referred patients (n = 46; median age 59 years; interquartile range: 46 to 68 years; 33% women) underwent both conventional echocardiography and CMR. CMR diastolic transmitral velocities (E and A) and myocardial tissue velocity (e') were measured during breath-hold using a validated high-temporal resolution radial sector-wise golden-angle velocity-encoded sequence. CMR pulmonary artery pressure was estimated from 4-dimensional flow analysis of blood flow vortex duration in the pulmonary artery. CMR left atrial volume was measured using the biplane long-axis area-length method. Both CMR and echocardiographic data were used to perform blinded grading of DD according to the 2016 joint American and European recommendations.
Results: Grading of DD by CMR agreed with that by echocardiography in 43 of 46 cases (93%), of which 9% were normal, 2% indeterminate, 63% grade 1 DD, 4% grade 2 DD, and 15% grade 3 DD. There was a very good categorical agreement, with a weighted Cohen kappa coefficient of 0.857 (95% confidence interval: 0.73 to 1.00; p < 0.001).
Conclusions: A comprehensive CMR protocol for grading DD encompassing diastolic blood and myocardial velocities, estimated pulmonary artery pressure, and left atrial volume showed very good agreement with echocardiography.
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| http://dx.doi.org/10.1016/j.jcmg.2020.06.027 | DOI Listing |
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