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Antimicrobial resistance related knowledge, attitude and practice of general practitioners, patients and farmers: A cross-sectional study in Uzbekistan.
Heliyon
October 2024
Heidelberg Institute of Global Health, Heidelberg, Germany, Neuenheimer Feld 672, 69120, Heidelberg, Germany.
Article Synopsis
- The study aimed to identify gaps in knowledge, attitudes, and practices regarding antimicrobial resistance among general practitioners, patients, and farmers in Uzbekistan.
- A survey conducted from March to October 2020 revealed significant issues, with 66.5% of general practitioners not following prescription guidelines, and misconceptions among patients and farmers about antibiotics' effectiveness and uses.
- The findings indicate a need for targeted interventions and training to improve understanding and practices related to antimicrobials among these groups.
Changing the Landscape of Solid Tumor Therapy from Apoptosis-Promoting to Apoptosis-Inhibiting Strategies.
Curr Issues Mol Biol
May 2024
Department of Oncology, Cross Cancer Institute, University of Alberta, Edmonton, AB T6G 1Z2, Canada.
The many limitations of implementing anticancer strategies under the term "precision oncology" have been extensively discussed. While some authors propose promising future directions, others are less optimistic and use phrases such as illusion, hype, and false hypotheses. The reality is revealed by practicing clinicians and cancer patients in various online publications, one of which has stated that "in the quest for the next cancer cure, few researchers bother to look back at the graveyard of failed medicines to figure out what went wrong".
View Article and Find Full Text PDFA Personalized Mediterranean Diet Improves Pain and Quality of Life in Patients with Fibromyalgia.
Pain Ther
June 2024
Neurophysiopathology Unit, DiBrain Department, Policlinico General Hospital, Bari Aldo Moro University, Piazza Giulio Cesare 11, 70124, Bari, Italy.
Introduction: Fibromyalgia is a form of chronic pain that affects a large number of women. It can start at any age and last a lifetime, with no cure. The Mediterranean diet is said to have an anti-inflammatory effect.
View Article and Find Full Text PDFPeriprosthetic bacterial and fugal infection after total knee arthroplasty with one-stage debridement: a case report.
J Med Case Rep
April 2024
Department of Joint Surgery, Qilu Hospital of Shandong University (Qingdao), Qingdao, 266000, Shandong, China.
Background: Periprosthetic infection is a serious complication after arthroplasty and is characterized by a long duration, recurrence, and a low cure rate. Although fungal infections are infrequent, they are often catastrophic, with an insidious onset, a long duration, atypical clinical symptoms, and imaging features in the early stage. They are easily misdiagnosed, or the diagnosis is missed, resulting in wrong treatment approaches.
View Article and Find Full Text PDFA Retrospective Cohort of Tumor-Induced Osteomalacia and Case Series of Malignant Disease.
J Clin Endocrinol Metab
January 2025
Division of Endocrinology and Metabolism, Department of Medicine, Mayo Clinic Rochester, Rochester, MN 55905, USA.
Context: Tumor-induced osteomalacia (TIO) is a rare condition with evidence mostly derived from case reports and case series.
Objective: We aimed to describe the clinical characteristics of a large cohort of patients diagnosed with TIO, with a focus on patients with nonlocalizing and malignant TIO.
Methods: This is a retrospective cohort of patients with TIO in an academic medical center, diagnosed between January 1998 and May 2023.
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