The concept of Ca2+ regulation, first discovered and developed in muscle research, is historically surveyed. Ca2+ regulation mechanisms in actomyosin-dependent contractile processes are compared, emphasis being placed on the great diversity. The mode of action of Ca2+ is discussed with the examples of troponin and calmodulin, the most differentiated and conservative Ca2+-receptor proteins, respectively.
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http://dx.doi.org/10.1016/0301-4622(88)87033-9 | DOI Listing |
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