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http://dx.doi.org/10.1016/j.vgie.2020.04.019DOI Listing

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Background And Aims: Difficult biliary cannulation (DBC) is a marker for prolonged procedure time and increased adverse event rate (AER) during endoscopic retrograde cholangiopancreatography (ERCP). We previously showed that EUS-guided rendezvous procedure (EUS-RV) had a higher single session success rate than precut papillotomy (PcP) in DBC patients. The present randomized study aims at comparing the technical success and AER between the two approaches.

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Background: Needle-knife precut papillotomy (NKP) is typically performed freehand. However, it remains unclear whether pancreatic stent (PS) placement can improve the outcomes of NKP.

Aim: To explore whether PS placement improves the success rate of NKP in patients with difficult biliary cannulation.

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Article Synopsis
  • ERCP is a medical procedure that can have some risks, including a condition called post-ERCP pancreatitis (PEP), which can happen when the procedure is tough to do.
  • A study with over 1,500 patients looked at whether doing an early cut (precut technique) helps lower the chances of getting PEP compared to a delayed cut.
  • The results showed that early precut patients had a lower risk of PEP (3.5%) compared to those who had a delayed cut (10.5%), and using a pancreatic stent during the delayed cut can help reduce PEP risk even more.
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Article Synopsis
  • Endoscopic retrograde cholangiopancreatography (ERCP) is crucial for treating biliary and pancreatic diseases, with needle-knife fistulotomy (NKF) and papillotomy (NKP) being common rescue techniques for challenging cases.
  • A meta-analysis of four studies involving 823 patients found no significant difference in success rates for biliary cannulation between NKF (91.7%) and NKP (86.9%), but NKF had a significantly lower rate of adverse events.
  • Overall, both NKF and NKP show similar effectiveness, but NKF appears to be safer in terms of complications.
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Article Synopsis
  • A 74-year-old woman with acute calculous cholangitis underwent ERCP and a pancreatic stent (PS) was placed to prevent post-ERCP pancreatitis after difficult cannulation.
  • During the procedure, an endoscopic papillary balloon dilation caused the stent to migrate into the main pancreatic duct (MPD).
  • The migrated stent was successfully removed in a follow-up ERCP two days later, highlighting the potential risks of stent migration with early placement during ERCP procedures.
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