We present an algorithm, and its MATLAB implementation, based on mathematical methods to detect and localize 3D multicolor DNA FISH spots in fluorescence cell image z-stacks. This algorithm provides a method to measure the relative positioning of spots in the nucleus and inter-spot distances with the aim to enrich our understanding of the 3D spatial organization of the genome within the cell nucleus.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/978-1-0716-0664-3_17 | DOI Listing |
Publication Analysis
Top Keywords
spatial organization
8
organization genome
8
algorithm analysis
4
analysis spatial
4
genome algorithm
4
algorithm matlab
4
matlab implementation
4
implementation based
4
based mathematical
4
mathematical methods
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!