Nocardia takedensis was first isolated in 2005, from soil in Japan. We report here two cases of lymphangitis in France (2012-2017) caused by N. takedensis both occurring after skin injury while gardening, which enabled its inoculation. The two patients were immunocompromised and successfully treated by an antimicrobial agent active on the isolated strain, trimethoprim-sulfamethoxazole and amoxicillin-clavulanic acid for patient one and patient two, respectively. Our study along with previous ones supports the idea of a newly recognized cutaneous opportunistic pathogen and reinforces the recommendation of using gloves during soil exposure for immunocompromised patients. Lastly, according to data found in the literature, we would recommend trimethoprim-sulfamethoxazole as an efficient empirical antibiotic therapy in case of cutaneous infection caused by N. takedensis.
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http://dx.doi.org/10.1186/s12941-020-00379-7 | DOI Listing |
Int J Syst Evol Microbiol
June 2019
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, PR China.
A novel actinobacterium, designated strain NEAU-351, was isolated from cow dung collected from Shangzhi, Heilongjiang Province, northeast PR China and characterized using a polyphasic approach. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain NEAU-351 belonged to the genus , with the highest similarity (98.96 %) to DSM 44801 and less than 98.
View Article and Find Full Text PDFAnn Clin Microbiol Antimicrob
August 2020
Department of Bacteriology, Nice Academic Hospital, Nice, France.
Nocardia takedensis was first isolated in 2005, from soil in Japan. We report here two cases of lymphangitis in France (2012-2017) caused by N. takedensis both occurring after skin injury while gardening, which enabled its inoculation.
View Article and Find Full Text PDFInt J Syst Evol Microbiol
October 2020
Leibniz Institute for Natural Product Research and Infection Biology e. V., Hans-Knöll-Institute, Beutenbergstraße 11a, 07745 Jena, Germany.
The taxonomic positions of two novel aerobic, Gram-stain-positive Actinobacteria, designated RB20 and RB56, were determined using a polyphasic approach. Both were isolated from the fungus-farming termite . Results of 16S rRNA gene sequence analysis revealed that both strains are members of the genus with the closest phylogenetic neighbours JCM12860 (98.
View Article and Find Full Text PDFAnn Dermatol
August 2017
Department of Dermatology, Kosin University College of Medicine, Busan, Korea.
species are aerobic, gram-positive, filamentous, partially acid-fast actinomycetes which are found worldwide in soil and decaying organic plant matter. When they infect human beings, they generally enter through the respiratory tract and then disseminate systemically. Rarely has a primary infection occurred as the result of direct inoculation.
View Article and Find Full Text PDFJAAD Case Rep
May 2015
Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
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