Strepyrazinone (, a tricyclic diketopiperazine derivative with a carbon skeleton unprecedented in natural products, was isolated from the marine-derived sp. B223. Its structure was elucidated by spectroscopic analyses and electronic circular dichroism calculation. Compound showed cytotoxic activity against HCT-116 cancer cell lines with an IC value of 0.34 µM.
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http://dx.doi.org/10.1080/10286020.2020.1801649 | DOI Listing |
J Asian Nat Prod Res
October 2021
School of Pharmacy, Binzhou Medical University, Yantai 264003, China.
Strepyrazinone (, a tricyclic diketopiperazine derivative with a carbon skeleton unprecedented in natural products, was isolated from the marine-derived sp. B223. Its structure was elucidated by spectroscopic analyses and electronic circular dichroism calculation.
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