Detection of protein-protein interactions (PPIs) is limited by current bioanalytical methods. A protein complementation assay (PCA), split TEM-1 β-lactamase, interacts with xenon at the interface of the TEM-1 fragments. Reconstitution of TEM-1-promoted here by cFos/cJun leucine zipper interaction-gives rise to sensitive 129Xe NMR signal in bacterial cells.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511426 | PMC |
| http://dx.doi.org/10.1039/d0cc02988b | DOI Listing |
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