In this issue of JEM, Recouvreux et al. (https://doi.org/10.1084/jem.20200388) describe the role of nutrient sensing in the induction of epithelial-mesenchymal transition. Glutamine-deficient pancreatic cancer cells up-regulate classic EMT regulator Slug, providing a link between nutrient stress and metastasis.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478736 | PMC |
http://dx.doi.org/10.1084/jem.20200819 | DOI Listing |
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