Inspiratory muscle training (IMT) and functional IMT (IMT: exercise-specific IMT activities) has been unsuccessful in reducing respiratory muscle fatigue following load carriage. IMT did not include load carriage specific exercises. Fifteen participants split into two groups (training and control) walked 6km loaded (18.2kg) at speeds representing ∼50%V̇O in cold-hypoxia. The walk was completed at baseline; post 4weeks IMT and 4weeks IMT (five exercises engaging core muscles, three involved load). The training group completed IMT and IMT at a higher maximal inspiratory pressure (P) than controls. Improvements in P were greater in the training group post-IMT (20.4%, =.025) and post-IMT (29.1%, =.050) compared to controls. Respiratory muscle fatigue was unchanged ( =.643). No other physiological or subjective measures were improved by IMT or IMT. Both IMT and IMT increased the strength of respiratory muscles pre-and-post a 6km loaded walk in cold-hypoxia. To explore the interaction between inspiratory muscle training (IMT), load carriage and environment, this study investigated 4weeks IMT and 4weeks functional IMT on respiratory muscle strength and fatigue. Functional IMT improved inspiratory muscle strength pre-and-post a loaded walk in cold-hypoxia but had no more effect than IMT alone. ANOVA: analysis of variance; BF: breathing frequency; CON: control group; EELV: end-expiratory lung volume; EXP: experimental group; FEV: forced expiratory volume in one second; FiO: fraction of inspired oxygen; FVC: forced vital capacity; HR: heart rate; IMT: inspiratory muscle training; IMT: functional inspiratory muscle training; P: maximal expiratory pressure; P: maximal inspiratory pressure; RMF: respiratory muscle fatigue; RPE: rate of perceived exertion; RWU: respiratory muscle warm-up; SaO: arterial oxygen saturation; SpO: peripheral oxygen saturation; V̇E: minute ventilation; V̇O: rate of oxygen uptake.
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http://dx.doi.org/10.1080/00140139.2020.1807613 | DOI Listing |
Am J Cardiovasc Dis
December 2024
Department of Cardiovascular Surgery, School of Medicine, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences Tehran, Iran.
Objectives: Postoperative pulmonary complications (POPC) are common after cardiac surgeries such as coronary artery bypass grafting (CABG) and are influenced by factors including anesthesia and surgical trauma. Inspiratory muscle training (IMT) with visual biofeedback may mitigate these complications. This study investigates the impact of threshold loading inspiratory muscle training (TL-IMT) combined with respiratory biofeedback on the dynamic strength of inspiratory muscles (S-index) in patients undergoing CABG surgery during their hospitalization phase.
View Article and Find Full Text PDFDrugs R D
January 2025
Research Division, Federal Institute of Drugs and Medical Devices (BfArM), Kurt-Georg-Kiesinger-Allee 3, 53175, Bonn, Germany.
Introduction: In November 2018, the European Medicines Agency (EMA) restricted the use of fluoroquinolones (used by mouth, injections or inhalation) in the context of a referral due to long-lasting and potentially irreversible adverse drug reactions (ADRs). Fluoroquinolones should no longer be used to treat mild or moderate bacterial infections unless other antibacterials cannot be used.
Objectives: The first aim of our study was to analyze whether in the period before compared with after the referral the characteristics of spontaneous ADR reports related to fluoroquinolones differed and whether specific ADRs were more frequently reported for fluoroquinolones compared with cotrimoxazole.
PLoS One
January 2025
Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Army Medical University, Chongqing, P. R. China.
Aim: To comprehensively investigate the effects of antioxidant nutrients on muscle mass, strength and function in chronic obstructive pulmonary disease (COPD) patients.
Methods: PubMed, Embase, Cochrane Library, and Web of Science were comprehensively searched from the inception to January 3, 2024. The quality of randomized controlled trials (RCTs) was measured using the Jadad scale.
Nurs Crit Care
January 2025
Department of Intensive Care Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.
Background: Tracheal extubation failure after cardiac surgery is associated with diminished cough strength, albeit the information on cough strength in post-cardiac surgery patients is limited.
Aim: To investigate the cough strength in patients after cardiac surgery before tracheal extubation and the related influencing factors.
Study Design: A cross-sectional study was designed, with adherence to the STROBE guidelines.
BMJ Open
December 2024
Department of Rehabilitation, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China
Introduction: Cystic fibrosis (CF) is an autosomal recessive genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, primarily affecting the respiratory and digestive systems. Respiratory rehabilitation techniques play a crucial role in managing pulmonary symptoms and maintaining lung function in CF patients. Although various techniques have been developed and applied, there is currently no globally recognised optimal respiratory rehabilitation regimen.
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