Endocardial-Epicardial Dissociation in Persistent Atrial Fibrillation: Driver or Bystander Activation Pattern?

Circ Arrhythm Electrophysiol

Department of Biomedical Engineering (K.N.A., N.A.T.), Johns Hopkins University, Baltimore, MD.

Published: August 2020

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440687PMC
http://dx.doi.org/10.1161/CIRCEP.120.009110DOI Listing

Publication Analysis

Top Keywords

endocardial-epicardial dissociation
4
dissociation persistent
4
persistent atrial
4
atrial fibrillation
4
fibrillation driver
4
driver bystander
4
bystander activation
4
activation pattern?
4
endocardial-epicardial
1
persistent
1

Similar Publications

Site-Specific Epicardium-to-Endocardium Dissociation of Electrical Activation in a Swine Model of Atrial Fibrillation.

JACC Clin Electrophysiol

July 2020

Section of Cardiac Electrophysiology, Department of Medicine, University of California-San Francisco, San Francisco, California, USA. Electronic address:

Objectives: This study sought to define the extent and spatial distribution of endocardial-epicardial dissociation (EED) in a swine model.

Background: The mechanisms underlying persistent atrial fibrillation (AF) remain unclear.

Methods: Sixteen swine underwent simultaneous endocardial and epicardial mapping using 32-electrode grid catheters.

View Article and Find Full Text PDF

Background: Endocardial-epicardial dissociation and focal breakthroughs in humans with atrial fibrillation (AF) have been recently demonstrated using activation mapping of short 10-second AF segments. In the current study, we used simultaneous endo-epi phase mapping to characterize endo-epi activation patterns on long segments of human persistent AF.

Methods: Simultaneous intraoperative mapping of endo- and epicardial lateral right atrium wall was performed in patients with persistent AF using 2 high-density grid catheters (16 electrodes, 3 mm spacing).

View Article and Find Full Text PDF

Background: The 3-dimensional (3D) nature of sinoatrial node (SAN) function has not been characterized in the intact human heart.

Objective: The purpose of this study was to characterize the 3D nature of SAN function in patients with structural heart disease (SHD) using simultaneous endocardial-epicardial (endo-epi) phase mapping.

Methods: Simultaneous intraoperative endo-epi SAN mapping was performed during sinus rhythm at baseline (SR) and postoverdrive suppression at 600 ms (SR) and 400 ms (SR) using 2 Abbott Advisor HD Grid Mapping Catheters.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!