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Pemphigus Foliaceus Mimicking Ichthyosis: A Rare Clinical Presentation.
Cureus
November 2024
Dermatology, Amiri Hospital, Ministry of Health, Kuwait City, KWT.
Pemphigus foliaceus (PF) is an autoimmune blistering disease characterized by the disruption of the epidermal cell adhesion protein desmoglein 1 (DsG1). PF classically presents with superficial erosions or blisters, but can rarely mimic other dermatological conditions, which makes diagnosis challenging. We report the case of a 57-year-old Sri Lankan man with a one-month history of widespread ichthyosis-like plaques and scales which started on his scalp and progressed in a cranio-caudal fashion and were associated with pruritus and few blisters.
View Article and Find Full Text PDFRetroperitoneal unicentric Castleman disease presenting with paraneoplastic pemphigus.
BMJ Case Rep
December 2024
General Surgery, PGIMER, Chandigarh, India.
Castleman disease is a benign lymph node hyperplasia with two histological subtypes. In the case reported here, a young adult male presented with mucocutaneous lesions mimicking common dermatological conditions. Suspicion of an underlying systemic disease arose when the routine clinical care of the skin lesions failed to cure them.
View Article and Find Full Text PDFCurrent Knowledge on Nail Involvement in Autoimmune Bullous Disorders.
Skin Appendage Disord
October 2024
Dermatology Departement, Saint Pierre and Brugmann University Hospitals, Université Libre de Bruxelles, Brussels, Belgium.
Article Synopsis
- Nail involvement in autoimmune bullous disorders presents diverse symptoms, often differing from skin manifestations, such as paronychia, onychomadesis, and onycholysis without blisters.
- Various autoimmune conditions like pemphigus vulgaris and bullous pemphigoid can cause nail changes, and the presence of Langerhans cells in the nails is noteworthy due to its unique immunological aspects.
- Diagnosing these nail issues typically requires histopathological and immunofluorescence tests, and researchers stress the need for more studies to improve treatment strategies for affected individuals.
Localized facial pemphigus foliaceus presenting in a dermatomal distribution: A case report.
SAGE Open Med Case Rep
September 2024
Division of Dermatology, CHU de Québec, Laval University, Quebec, Canada.
Article Synopsis
- Pemphigus foliaceus is an autoimmune skin disorder that causes superficial blisters.
- Localized cases are extremely rare, with very few documented instances.
- This report describes the first known case of an 81-year-old man with localized pemphigus foliaceus that appeared as dermatomal facial lesions, highlighting the diagnostic challenges due to its atypical presentation.
Solitary verrucous plaque on a leg.
Int J Dermatol
February 2025
Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Article Synopsis
- A 70-year-old woman had a single wart-like growth on her leg and painful sores in her mouth.
- Doctors considered possible conditions like lichen simplex chronicus and chromoblastomycosis before diagnosing her with pemphigus vegetans (PVeg).
- This case emphasizes the need to include PVeg in diagnoses for unusual skin growths, even when they appear in unexpected areas of the body.
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