Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.jafc.0c04760 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
[Correction of the effect of vitamin K antagonists and antiplatelet agents in hemorrhagic stroke].
Zh Vopr Neirokhir Im N N Burdenko
December 2024
Burdenko Neurosurgical Center, Moscow, Russia.
Background: Hemorrhagic stroke (HS) is associated with high risk of mortality or disability. To date, up to 25% of HSs are associated with anticoagulants and antiplatelet agents. Early hemostatic therapy and correction of effect of antithrombotic drugs in patients with HS significantly reduce the risk of adverse outcomes.
View Article and Find Full Text PDFDivide and conquer: using RhizoVision Explorer to aggregate data from multiple root scans using image concatenation and statistical methods.
New Phytol
December 2024
Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37830, USA.
Article Synopsis
- Roots play a crucial role in agricultural productivity and soil carbon inputs, but measuring them can be complicated when samples are too large for a single scan.
- This study introduces and validates two approaches for standardizing root measurements across multiple scans: image concatenation and statistical aggregation, using custom Python and R scripts.
- The comparison of these methods on various plant species indicated that most root metrics were similar, except for median diameter, which is better measured through concatenation, thus benefiting the root biology community.
The safety of available pharmacotherapy for stroke prevention in atrial fibrillation.
Expert Opin Drug Saf
November 2024
Cardiology Clinic, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, Padua University Hospital, Padua, Italy.
Introduction: Oral anticoagulant drugs reduce the risk of stroke associated with atrial fibrillation. Vitamin K antagonists, gold standard therapy for decades, have been deposed by the direct oral anticoagulants that exhibit superior safety profiles. However, hemorrhagic complications remain a major concern to anticoagulation.
View Article and Find Full Text PDFBromadiolone may cause severe acute kidney injury through severe disorder of coagulation: a case report.
BMC Nephrol
September 2024
Department of Nephrology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Article Synopsis
- Bromadiolone is a long-acting anticoagulant rodenticide that can lead to serious coagulation issues, but cases of acute kidney injury (AKI) due to its poisoning haven't been reported until now.
- A 27-year-old woman developed severe coagulopathy and AKI after bromadiolone exposure, indicating a vitamin K deficiency; her kidney function worsened but later fully recovered with treatment.
- This case highlights that bromadiolone can cause AKI through severe coagulation dysfunction, which can be treated effectively with high doses of vitamin K and plasma transfusion.
Rapid diagnosis of coagulopathies from vitamin K deficiency in a consecutive case cohort evaluated by comparative assessment of factor II by 1-stage assays with prothrombin time vs Ecarin reagents.
J Thromb Haemost
November 2024
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada; Division of Hematology & Thromboembolism, Department of Medicine, McMaster University, Hamilton, Ontario, Canada; Hematology, Hamilton Health Sciences, Hamilton, Ontario, Canada; Hematology, Hamilton Regional Laboratory Medicine Program, Hamilton, Ontario, Canada. Electronic address:
Background: Vitamin K (VK) deficiency (VKD) impairs γ-carboxylation of VK-dependent factors (VKDFs), resulting in higher factor (F)II levels measured by Ecarin (FIIE) reagents (that convert des-γ-carboxylated FII to meizothrombin) than by prothrombin time (FII) reagents.
Objectives: To evaluate FII/FIIE abnormalities among patients assessed for coagulopathies and identify findings predictive of coagulopathy improvement after VK.
Methods: We retrospectively assessed consecutive cases from 2002 to 2021 with FII/FIIE tests and the sensitivity and specificity of FII/FIIE ratios and FIIE-FII differences for VKD defined as international normalized ratio correction/improvement of ≥0.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!