Empirical networks are often globally sparse, with a small average number of connections per node, when compared to the total size of the network. However, this sparsity tends not to be homogeneous, and networks can also be locally dense, for example, with a few nodes connecting to a large fraction of the rest of the network, or with small groups of nodes with a large probability of connections between them. Here we show how latent Poisson models that generate hidden multigraphs can be effective at capturing this density heterogeneity, while being more tractable mathematically than some of the alternatives that model simple graphs directly. We show how these latent multigraphs can be reconstructed from data on simple graphs, and how this allows us to disentangle disassortative degree-degree correlations from the constraints of imposed degree sequences, and to improve the identification of community structure in empirically relevant scenarios.
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http://dx.doi.org/10.1103/PhysRevE.102.012309 | DOI Listing |
Variational autoencoders (VAEs) employ Bayesian inference to interpret sensory inputs, mirroring processes that occur in primate vision across both ventral (Higgins et al., 2021) and dorsal (Vafaii et al., 2023) pathways.
View Article and Find Full Text PDFSex Res Social Policy
August 2023
Division of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA USA.
Introduction: Drug use behaviors are closely associated with increased risk for HIV and other STIs among men who have sex with men (MSM) globally. Less is known about the drug use characteristics and their association with HIV/STI risk among MSM in Mexico, who have 13 times higher risk of acquiring HIV than the general population. We characterized distinct classes of drug use behaviors among a nationwide sample of MSM in Mexico and tested their associations with HIV risk behaviors.
View Article and Find Full Text PDFAm J Ind Med
February 2025
Brussels Institute for Social and Population Studies (BRISPO), Vrije Universiteit Brussel, Brussels, Belgium.
Background: The typological approach of the employment quality (EQ) framework offers a comprehensive lens for assessing the heterogeneity of employment experiences while concurrently acknowledging associated health risk factors. EQ incorporates multiple employment characteristics-such as working hours, wages and benefits, and union representation, among others-where standard employment relationship (SER)-like (or high EQ) features are distinguished from nonstandard features (low EQ). Low EQ features are known to relate negatively to health outcomes.
View Article and Find Full Text PDFStat Methods Med Res
December 2024
Programa de Computação Científica (PROCC), Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
In disease mapping, the relative risk of a disease is commonly estimated across different areas within a region of interest. The number of cases in an area is often assumed to follow a Poisson distribution whose mean is decomposed as the product between an offset and the logarithm of the disease's relative risk. The log risk may be written as the sum of fixed effects and latent random effects.
View Article and Find Full Text PDFJ Infect Dis
December 2024
Amsterdam UMC, location University of Amsterdam, Department of Infectious Diseases, Meibergdreef 9, Amsterdam, The Netherlands.
Background: People with HIV (PWH) experience a higher burden of ageing-associated comorbidities, the underlying mechanisms of which remain to be fully elucidated. We aimed to identify profiles based on immune, inflammatory, and ageing biomarkers in blood from PWH and controls, and explore their association with total comorbidities over time.
Methods: Latent profile analysis was used to construct biomarker profiles in AGEhIV cohort participants (94 with well-controlled HIV on antiretroviral therapy (ART) and 95 controls without HIV) using baseline measurements of selected biomarkers.
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