Immunofluorescent techniques were used in the study of tissue from a patient with pemphigus vegetans of Hallopeau. The findings were typical of pemphigus, confirming the propriety of classifying this entity as a benign variant of pemphigus, rather than a disease of purely microbial etiology. The question is raised whether other types of vegetating pyodermas actually are separate diseases or represent a spectrum of pemphigus with the clinical appearance dependent on the patient's immunity to his disease. Immunofluorescent studies are proposed as a basis for classification.

Download full-text PDF

Source

Publication Analysis

Top Keywords

pemphigus vegetans
8
vegetans hallopeau
8
immunofluorescent studies
8
pemphigus
5
hallopeau immunofluorescent
4
studies immunofluorescent
4
immunofluorescent techniques
4
techniques study
4
study tissue
4
tissue patient
4

Similar Publications

Article Synopsis
  • The study focuses on vulvar acantholytic dyskeratoses, which are rare skin conditions affecting the vulva and perineum, with a goal to improve classification and understanding for gynecologic pathologists.
  • Between 1990 and 2023, 16 cases of vulvar acantholytic dyskeratoses were analyzed, mostly affecting women aged 36 to 79, with many presenting asymptomatic or pruritic lesions predominantly on the labia majora.
  • Histologically, these conditions showed features like acantholysis, with some patients responding to local excision or corticosteroids; however, no clear distinction was found between sporadic and syndromic cases based on
View Article and Find Full Text PDF
Article Synopsis
  • A 70-year-old woman had a single wart-like growth on her leg and painful sores in her mouth.
  • Doctors considered possible conditions like lichen simplex chronicus and chromoblastomycosis before diagnosing her with pemphigus vegetans (PVeg).
  • This case emphasizes the need to include PVeg in diagnoses for unusual skin growths, even when they appear in unexpected areas of the body.
View Article and Find Full Text PDF

Pemphigus vegetans is a rare type of pemphigus characterized by vegetative lesions primarily localized to the intertriginous area. Despite its unique clinical presentation, the underlying pathomechanism remains unclear owing to the rarity of the disease. We report a case of pemphigus vegetans with antibodies against desmoglein 1 and desmocollins 1-3.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!