Immunofluorescent techniques were used in the study of tissue from a patient with pemphigus vegetans of Hallopeau. The findings were typical of pemphigus, confirming the propriety of classifying this entity as a benign variant of pemphigus, rather than a disease of purely microbial etiology. The question is raised whether other types of vegetating pyodermas actually are separate diseases or represent a spectrum of pemphigus with the clinical appearance dependent on the patient's immunity to his disease. Immunofluorescent studies are proposed as a basis for classification.
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Indian Dermatol Online J
July 2024
Department of Dermatology, SRIHER, Chennai, Tamil Nadu, India.
Int J Gynecol Pathol
August 2024
Department of Pathology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan.
Int J Dermatol
August 2024
Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
J Dermatol
December 2024
Department of Dermatology, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.
Pemphigus vegetans is a rare type of pemphigus characterized by vegetative lesions primarily localized to the intertriginous area. Despite its unique clinical presentation, the underlying pathomechanism remains unclear owing to the rarity of the disease. We report a case of pemphigus vegetans with antibodies against desmoglein 1 and desmocollins 1-3.
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